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Sulfated Hyaluronic Acids

Maintaining the undifferentiated state of hiPS cell

Maintaining the undifferentiated state of hiPS cell

Sulfated hyaluronic acid maintains the undifferentiated state of hiPS cells underfeeder-free and bFGF-free conditions.


These data were kindly provided by Prof. Shoko Nishihara and Dr. Taichi Miura, Soka University.

Reference

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Stabilization of bFGF

Stabilization of bFGF by Sulfated Hyaluronic Acid

Low- and high- sulfated hyaluronic acid were individually added to bFGF and incubated at 37°C for 3 days,
followed by SDS-PAGE and image analysis to calculate the bFGF content.

High-sulfated hyaluronic acid has a greater capacity to preserve bFGF than heparin.

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