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CAS RN: 280744-09-4 | Product Number: B5716

SB 216763


Purity: >98.0%(HPLC)
Synonyms:
  • 3-(2,4-Dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione
Documents:
10MG
₩ 216,000
9   ≥20 
50MG
₩ 643,200
18   2  
* Please contact our distributor of SEJIN CI Co., Ltd. if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination.
* SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:  sales@sejinci.co.kr)

Product Number B5716
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__1__9H__1__2Cl__2N__2O__2 = 371.22  
Physical State (20 deg.C) Solid
Storage Temperature <0°C
Condition to Avoid Heat Sensitive
CAS RN 280744-09-4
Reaxys Registry Number 11333014
PubChem Substance ID 354335732
MDL Number

MFCD09753369

Specifications
Appearance Light yellow to Brown powder to crystal
Purity(HPLC) min. 98.0 area%
Properties (reference)
Melting Point 104 °C
GHS
Related Laws:
Transport Information:
H.S.code* 2933.99-000
*This code is applied to the products when TCI exports from Japan and not for import in your country.
Application
SB 216763: An ATP-Competitive Inhibitor of GSK-3α

SB 216763 is reportedly an ATP-competitive inhibitor of glycogen synthase kinase-3α (GSK-3α) in vitro with an IC50 value of 34 nM. GSK-3 is a serine/threonine protein kinase, and inhibition of its activity has been proposed to play a role in the regulation of numerous signalling pathways that elicit cellular responses.

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