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CAS RN: 31282-04-9 | Product Number: H1509
Hygromycin B
Purity: >80.0%(HPLC)
Synonyms:
Documents:
Size | Unit Price | Same Day | 2-3 Business Days |
---|---|---|---|
200MG |
₩ 49,600
|
≥20 | 12 |
1G |
₩ 168,000
|
≥20 | 7 |
* Please contact our distributor of SEJIN CI
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination.
* SEJIN CI (Phone: 02-2655-2480 / email: sales@sejinci.co.kr)
* SEJIN CI (Phone: 02-2655-2480 / email: sales@sejinci.co.kr)
Product Number | H1509 |
Purity / Analysis Method | >80.0%(HPLC) |
Molecular Formula / Molecular Weight | C__2__0H__3__7N__3O__1__3 = 527.52 |
Physical State (20 deg.C) | Solid |
Storage Temperature | 0-10°C |
Condition to Avoid | Heat Sensitive |
CAS RN | 31282-04-9 |
Reaxys Registry Number | 66457 |
PubChem Substance ID | 253661073 |
Merck Index (14) | 4852 |
MDL Number | MFCD06795479 |
Specifications
Appearance | White to Light yellow to Dark green powder to crystal |
Purity(HPLC)(CAD) | min. 80.0 area% |
Specific rotation [a]20/D | +18.0 to +23.0 deg(C=1, H2O) |
Properties (reference)
Melting Point | 180 °C(dec.) |
Specific Rotation | 20° (C=1,H2O) |
Solubility in water | Completely soluble |
Solubility (very soluble in) | Ethanol,Methanol |
GHS
Pictogram |
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Signal Word | Danger |
Hazard Statements | H300 + H310 + H330 : Fatal if swallowed, in contact with skin or if inhaled. H318 : Causes serious eye damage. H317 : May cause an allergic skin reaction. H334 : May cause allergy or asthma symptoms or breathing difficulties if inhaled. |
Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P272 : Contaminated work clothing should not be allowed out of the workplace. P260 : Do not breathe dust/ fume/ gas/ mist/ vapors/ spray. P270 : Do not eat, drink or smoke when using this product. P262 : Do not get in eyes, on skin, or on clothing. P271 : Use only outdoors or in a well-ventilated area. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P284 : Wear respiratory protection. P342 + P311 : If experiencing respiratory symptoms: Call a POISON CENTER/doctor. P361 + P364 : Take off immediately all contaminated clothing and wash it before reuse. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P302 + P352 + P310 : IF ON SKIN: Wash with plenty of water. Immediately call a POISON CENTER/doctor. P304 + P340 + P310 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor. P305 + P351 + P338 + P310 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/doctor. P403 + P233 : Store in a well-ventilated place. Keep container tightly closed. P405 : Store locked up. |
Related Laws:
RTECS# | WK2130000 |
Transport Information:
UN Number | UN3462 |
Class | 6.1 |
Packing Group | I |
H.S.code* | 2941.90-000 |
Application
Hygromycin B: A Selective Reagent in Molecular Genetics Experiments on Cells
Hygromycin B is a water-soluble aminoglycoside antibiotic produced by the bacterium Streptomyces hygroscopicus. It is acts by binding to the 80S subunit of the bacterial ribosome and inhibiting protein synthesis. In molecular genetics, hygromycin B is used in genetic modification as a selective reagent to isolate prokaryotic and eukaryotic cells coupled to a gene coding for hygromycin resistance.
References
- Plasmid-encoded hygromycin B resistance: the sequence of hygromycin B phosphotransferase gene and its expression in Escherichia coli and Saccharomyces cerevisiae
- Hygromycin B phosphotransferase as a selectable marker for DNA transfer experiments with higher eucaryotic cells
- Resistance to hygromycin B. A new marker for plant transformation studies
- Transformation of Aspergillus based on the hygromycin B resistance marker from Escherichia coli
- Dominant positive and negative selection using a hygromycin phosphotransferase-thymidine kinase fusion gene
- Efficient soybean transformation using hygromycin B selection in the cotyledonary-node method
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