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CAS RN: 338967-87-6 | Product Number: M3108

Mdivi-1


Purity: >95.0%(HPLC)
Synonyms:
  • 3-(2,4-Dichloro-5-methoxyphenyl)-2-thioxo-2,3-dihydro-4(1H)-quinazolinone
Documents:
10MG
₩169,600
6   3  
50MG
₩587,200
≥20  3  
* Please contact our distributor of SEJIN CI if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination.
* SEJIN CI (Phone: 02-2655-2480 / email:  sales@sejinci.co.kr)

Product Number M3108
Purity / Analysis Method >95.0%(HPLC)
Molecular Formula / Molecular Weight C__1__5H__1__0Cl__2N__2O__2S = 353.22  
Physical State (20 deg.C) Solid
Storage Temperature -20°C
Condition to Avoid Heat Sensitive
CAS RN 338967-87-6
Reaxys Registry Number 23802926
PubChem Substance ID 354335750
MDL Number

MFCD00974506

Specifications
Appearance White to Light yellow powder to crystal
Purity(HPLC) min. 95.0 area%
Elemental analysis(Nitrogen) 7.50 to 8.50 %
Properties (reference)
Melting Point 289 °C
GHS
Related Laws:
Transport Information:
H.S.code* 2933.79-000
*This code is applied to the products when TCI exports from Japan and not for import in your country.
Application
Mdivi-1: A Selective Cell-Permeable Inhibitor of Mitochondrial Fission

Mitochondria play a key role in maintaining cellular metabolic homeostasis, and its fission and fusion play important roles in in several pathological conditions. Mitochondrial fission mediated by the GTPase dynamin-related protein 1 (Drp-1) is an attractive drug target in numerous maladies that range from heart disease to neurodegenerative disorders.
Mdivi-1 (mitochondrial division inhibitor 1) has been reported to inhibit selectively Drp-1 dependent fission with cell permeability. Inhibiting mitochondrial fission with Mdivi-1 has proven cytoprotective benefits in several cell types involved in a wide array of cardiovascular injury models. (The product is for research purpose only.)

References


PubMed Literature


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