Sulfated Hyaluronic Acids
Maintaining the undifferentiated state of hiPS cell
Sulfated hyaluronic acid maintains the undifferentiated state of hiPS cells underfeeder-free and bFGF-free conditions.
- Highly sulfated hyaluronic acid maintains human induced pluripotent stem cells under feeder-free and bFGF-free conditions
Stabilization of bFGF
Low- and high- sulfated hyaluronic acid were individually added to bFGF and incubated at 37°C for 3 days, followed by SDS-PAGE and image analysis to calculate the bFGF content.
High-sulfated hyaluronic acid has a greater capacity to preserve bFGF than heparin.