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CAS RN: 1405-10-3 | Product Number: F0649

Fradiomycin Sulfate


Purity: >97.0%(N)
Synonyms:
  • Neomycin Sulfate
Documents:
25G
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Product Number F0649
Purity / Analysis Method >97.0%(N)
Molecular Formula / Molecular Weight C__2__3H__4__6N__6O__1__3·3H__2SO__4 = 908.87  
Physical State (20 deg.C) Solid
Store Under Inert Gas Store under inert gas
Condition to Avoid Light Sensitive,Hygroscopic
CAS RN 1405-10-3
Related CAS RN 1404-04-2
Reaxys Registry Number 9468364
PubChem Substance ID 87560000
Merck Index (14) 6454
MDL Number

MFCD00077833

Specifications
Appearance White to Orange to Green powder to crystal
Purity(with Total Nitrogen) min. 97.0 %(calcd.on dried substance)  
Specific rotation [a]20/D +53.0 to +60.0 deg(C=10, H2O)(calcd.on dried substance)
Drying loss max. 8.0 %
Properties (reference)
Specific Rotation 56° (C=10,H2O)
Solubility in water Soluble
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H317 : May cause an allergic skin reaction.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P261 : Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray.
P272 : Contaminated work clothing should not be allowed out of the workplace.
P280 : Wear protective gloves.
P362 + P364 : Take off contaminated clothing and wash it before reuse.
P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention.
Related Laws:
EC Number 215-773-1
RTECS# QP4375000
Transport Information:
HS Number 2941900000
Application
Fradiomycin or Neomycin: A Broad Spectrum Aminoglycoside Antibiotic

Fradiomycin or neomycin, an aminoglycoside antibiotic, is first isolated in 1949 from the gram-positive bacillus Streptomyces fradiae. It consists of a mixture of two isomers, fradiomycin B and fradiomycin C. Fradiomycin has broad activity against Gram-negative bacteria except Pseudomonas aeruginosa and Gram-positive bacteria. It binds with bacterium ribosome 30s, and then it inhibits bacterial growth by inhibiting protein synthesis.

References


PubMed Literature


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