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CAS RN: 108321-42-2 | Product Number: G0349

G418 Disulfate


Purity: >90.0%(HPLC)(N)
Synonyms:
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Product Number G0349
Purity / Analysis Method >90.0%(HPLC)(N)
Molecular Formula / Molecular Weight C__2__0H__4__0N__4O__1__0·2H__2SO__4 = 692.70  
Physical State (20 deg.C) Solid
Storage Temperature 0-10°C
Condition to Avoid Heat Sensitive
CAS RN 108321-42-2
Related CAS RN 49863-47-0
PubChem Substance ID 125307225
MDL Number

MFCD00058314

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 90.0 area%
Purity(with Total Nitrogen) min. 90.0 %
Specific rotation [a]20/D +110 to +120 deg(C=0.3, H2O, calcd.on anh.substance)
Properties (reference)
Specific Rotation 111° (C=0.3,H2O)
GHS
Related Laws:
Transport Information:
HS Number 2941900000
Application
G418: A Selective Agent for Genetically Engineered Eukaryotic Cells

G418 is an aminoglycoside antibiotic similar in structure to gentamicin [G0383] and is frequently used to selective agent for genetically engineered eukaryotic cells after transfection or transduction. It binds with the 70s and 80s ribosomes, and then it inhibits eukaryotic cell growth by inhibiting protein synthesis.

References


PubMed Literature


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