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Published TCIMAIL newest issue No.201
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CAS RN: 27164-46-1 | Product Number: C2242
Cefazolin Sodium Salt
Purity: >98.0%(T)(HPLC)
Synonyms:
Product Documents:
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Supplemental Product Information:
This product has not been tested for potency and is guaranteed for chemical purity.
| Product Number | C2242 |
Purity / Analysis Method
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__4H__1__3N__8NaO__4S__3 = 476.48 |
| Physical State (20 deg.C) | Solid |
Storage Temperature
|
Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 27164-46-1 |
Related CAS RN
|
25953-19-9 |
| Reaxys Registry Number | 4229326 |
| PubChem Substance ID | 87560303 |
| Merck Index (14) | 1917 |
| MDL Number | MFCD00056883 |
Specifications
| Appearance | White to Orange to Green powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Specific rotation [a]20/D | -15.0 to -24.0 deg(C=10, H2O) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 190 °C |
| Specific Rotation | -20° (C=10,H2O) |
| Solubility (slightly sol. in) | Methanol, Ethanol |
| Solubility (insoluble in) | Chloroform, Acetone, Benzene |
GHS
Related Laws:
| EC Number | 248-278-4 |
| RTECS# | XI0390000 |
Transport Information:
| HS Number | 2941900000 |
Application
Cefazolin Sodium: A First-Generation Cephalosporin Antibiotic
Cefazolin sodium is a first-generation semisynthetic cephalosporin antibiotic, which is chemically synthesized form 7-aminocephalosporanic acid (7-ACA) [A1266], has been used worldwide since the early 1970s. It has a broad spectrum of activity against Gram-positive and Gram-negative bacteria. Recently, it has been reported it as a corrosion inhibitor for mild steel in hydrochloric acid solution.
References
- Cephalosporin. III. Cefazolin, a new semisynthetic cephalosporin antibiotic. I. Synthesis and chemical properties of cefazolin
- Cefazolin (on the physical properties, synthesis, stability, metabolism, and analysis of cefazolin
- Structural relationship and desolvation behavior of cromolyn, cefazolin and fenoprofen sodium hydrates
- Safety and efficacy of cefazolin sodium in the management of bacterial infection and in surgical prophylaxis
- Effect of Cefazolin on the corrosion of mild steel in HCl solution
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