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Published TCIMAIL newest issue No.201
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CAS RN: 5467-74-3 | Product Number: B1858
4-Bromophenylboronic Acid (contains varying amounts of Anhydride)
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Purity:
Synonyms:
- 4-Bromobenzeneboronic Acid (contains varying amounts of Anhydride)
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
17,00 €
|
Contact Us | ≥40 |
|
|
| 5G |
31,00 €
|
8 | ≥100 |
|
|
| 25G |
108,00 €
|
1 | ≥80 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | B1858 |
| Molecular Formula / Molecular Weight | C__6H__6BBrO__2 = 200.83 |
| Physical State (20 deg.C) | Solid |
Storage Temperature 
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 5467-74-3 |
| Reaxys Registry Number | 2936347 |
| PubChem Substance ID | 87564746 |
| SDBS (AIST Spectral DB) | 22866 |
| MDL Number | MFCD00002104 |
Specifications
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(Neutralization titration) | 97.0 to 110.0 % |
Properties (reference)
| Melting Point | 292 °C |
| Solubility (soluble in) | Methanol |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
| EC Number | 226-779-9 |
| RTECS# | CY8650000 |
Transport Information:
| HS Number | 2931900090 |
Application
Efflux pump research
4-Bromophenylboronic acid has been reported to act as an inhibitor of Staphylococcus aureus NorA efflux pump.1) The compound was found to potentiate ciprofloxacin activity by a 4-fold increase at concentrations ranging at 2-4 μg/ml against S. aureus 1199B, which overexpresses NorA.1)
(The product is for research purpose only.)
(The product is for research purpose only.)
Reference
- 1) First Identification of Boronic Species as Novel Potential Inhibitors of the Staphylococcus aureus NorA Efflux Pump
- β-Lactamases and β-Lactamase Inhibitors in the 21st Century
- Structure-Based Enhancement of Boronic Acid-Based Inhibitors of AmpC β-Lactamase
- Inhibition of Quorum Sensing in Vibrio harveyi by Boronic Acids
Application
AmpC β-lactamase inhibitor
The primary resistance mechanism of microbes to β-lactam antibiotics is hydrolysis of the antibiotics by β-lactamase.1) 4-Bromophenylboronic acid is one of boronic acid compounds having β-lactamase (AmpC) inhibition activity (Ki = 3.6 ± 0.9 μM).2)
References
Application
Quorum sensing research
4-Bromophenylboronic acid has been reported to inhibit autoinducer-2 (AI-2) quorum sensing in Vibrio harveyi.
Reference
PubMed Literature
Product Articles
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
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