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CAS RN: 6202-23-9 | Product Number: C3157
Cyclobenzaprine Hydrochloride
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Purity: >98.0%(T)(HPLC)
Synonyms:
- 5-(3-Dimethylaminopropylidene)dibenzo[a,e]cycloheptatriene Hydrochloride
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
27,00 €
|
1 | ≥80 |
|
|
| 5G |
94,00 €
|
2 | ≥80 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | C3157 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__2__0H__2__1N·HCl = 311.85 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 6202-23-9 |
| Related CAS RN
|
303-53-7 |
| Reaxys Registry Number | 6247987 |
| PubChem Substance ID | 253661206 |
| Merck Index (14) | 2713 |
| MDL Number | MFCD00079039 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 215.0 to 219.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 217 °C |
| Maximum Absorption Wavelength | 290 nm |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
| EC Number | 228-264-4 |
| RTECS# | HP0875000 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | III |
| HS Number | 2921490090 |
Application
Cyclobenzaprine Hydrochloride: A Muscle Relaxant Acting on the Central Nervous System
Cyclobenzaprine hydrochloride is a muscle relaxant acting primarily on the central nervous system, and is structurally similar to tricyclic antidepressants. It works by blocking nerve impulses (or pain sensations) that are sent to the brain. The exact mechanism of action is still not clear, while a research appears to indicate that it acts as a 5-HT2 receptor antagonist.
References
- Physiological disposition and metabolism of cyclobenzaprine in the rat, dog, rhesus monkey, and man
- Identification of human liver cytochrome P450 isoforms involved in the in vitro metabolism of cyclobenzaprine
- Cyclobenzaprine, a centrally acting muscle relaxant, acts on descending serotonergic systems
- Commonly used muscle relaxant therapies for acute low back pain: a review of carisoprodol, cyclobenzaprine hydrochloride, and metaxalone (a review)
- Development and comparison of high-performance liquid chromatographic methods with tandem mass spectrometric and ultraviolet absorbance detection for the determination of cyclobenzaprine in human plasma and urine
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