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Published TCIMAIL newest issue No.201
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CAS RN: 41354-29-4 | Product Number: C3218
Cyproheptadine Hydrochloride Sesquihydrate
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Purity: >98.0%(T)(HPLC)
Synonyms:
- 4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-methylpiperidine Hydrochloride Sesquihydrate
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 5G |
40,00 €
|
Contact Us | 7 |
|
|
| 25G |
125,00 €
|
Contact Us | 15 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | C3218 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__2__1H__2__1N·HCl·1^^1/__2H__2O = 350.88 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 41354-29-4 |
| Related CAS RN
|
969-33-5&129-03-3 |
| PubChem Substance ID | 354333357 |
| Merck Index (14) | 2773 |
| MDL Number | MFCD00012538 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 %(after drying) |
| Drying loss | 7.0 to 9.0 % |
Properties (reference)
| Maximum Absorption Wavelength | 285 nm (0.05mol/L H__2SO__4) |
| Solubility (soluble in) | Chloroform |
| Solubility (slightly sol. in) | Ethanol |
| Solubility (insoluble in) | Ether |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. |
Related Laws:
| EC Number | 213-535-1 |
| RTECS# | TM7050000 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | III |
| HS Number | 2933399999 |
Application
Cyproheptadine Hydrochloride: A Potent 5-HT Receptor and Histamine H1 Receptor Antagonist
Cyproheptadine hydrochloride is a 5-HT (serotonin, [S0370 (hydrochloride)]) receptor antagonist with antiserotonin activity comparable with that of LSD. In addition, it is histamine H1 receptor antagonist with potent antihistaminic activity. Meanwhile, it has anticholinergic effect as a side effect. (The product is for research purpose only.)
References
- Antiserotonin-antihistaminic properties of cyproheptadine
- Antimuscarinic effects of antihistamines: quantitative evaluation by receptor-binding assay
- Effects of 5-HT uptake inhibitors, agonists and antagonists on the burying of harmless objects by mice; a putative test for anxiolytic agents
- Comparative anticholinergic activities of 10 histamine H1 receptor antagonists in two functional models
- Cyproheptadine: A review on the description, physical properties, synthesis, metabolism and analysis of cyproheptadine-HCl
- HPLC and chemometric methods for the simultaneous determination of cyproheptadine hydrochloride, multivitamins, and sorbic acid
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