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Published TCIMAIL newest issue No.201
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CAS RN: 62004-35-7 | Product Number: L0309
LFM-A13
Purity: >98.0%(HPLC)
Synonyms:
- 2-Cyano-N-(2,5-dibromophenyl)-3-hydroxy-2-butenamide
Product Documents:
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| Product Number | L0309 |
Purity / Analysis Method
|
>98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__1H__8Br__2N__2O__2 = 360.01 |
| Physical State (20 deg.C) | Solid |
Storage Temperature
|
Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 62004-35-7 |
| Reaxys Registry Number | 10678941 |
| PubChem Substance ID | 354335753 |
| MDL Number | MFCD02179204 |
Specifications
| Appearance | Light yellow to Brown powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Elemental analysis(Nitrogen) | 7.30 to 8.20 % |
| NMR | confirm to structure |
Properties (reference)
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 + H312 + H332 : Harmful if swallowed, in contact with skin or if inhaled. H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P261 : Avoid breathing dust. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P302 + P352 + P312 : IF ON SKIN: Wash with plenty of water. Call a POISON CENTER/doctor if you feel unwell. P304 + P340 + P312 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell. |
Related Laws:
Transport Information:
| HS Number | 2926907090 |
Application
LFM-A13: A Potent and Selective Inhibitor of Bruton's Tyrosine Kinase (BTK)
LFM-A13 is reportedly a potent and selective inhibitor of Bruton's tyrosine kinase (BTK), and as an anti-leukemia agent with apoptosis-promoting and chemosensitizing properties. (The product is for research purpose only.)
References
- Rational design and synthesis of a novel anti-leukemic agent targeting Bruton's tyrosine kinase (BTK), LFM-A13 [α-cyano-β-hydroxy-β-methyl-N-(2,5-dibromophenyl)propenamide]
PubMed Literature
Product Articles
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Specifications
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