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Published TCIMAIL newest issue No.201
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CAS RN: 1722-62-9 | Product Number: M2560
Mepivacaine Hydrochloride
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Purity: >98.0%(T)(HPLC)
Synonyms:
- N-(2,6-Dimethylphenyl)-1-methyl-2-piperidinecarboxamide Hydrochloride
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
€ 89,00
|
1 | 3 |
|
|
| 5G |
€ 284,00
|
1 | 2 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | M2560 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__5H__2__2N__2O·HCl = 282.81 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 1722-62-9 |
| Reaxys Registry Number | 3734352 |
| PubChem Substance ID | 253662419 |
| MDL Number | MFCD00144738 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
Properties (reference)
| Melting Point | 263 °C |
| Solubility in water | Soluble |
| Solubility (soluble in) | Methanol |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| EC Number | 217-023-9 |
| RTECS# | TK6475000 |
Transport Information:
| HS Number | 2933399999 |
Application
Mepivacaine Hydrochloride: A Local Anesthetic of the Amide Type
Mepivacaine hydrochloride is a local anesthetic of the amide type which includes lidocain [L0156], mepivacaine hydrochloride [M2560], prilocaine hydrochloride [P2038], bupivacaine hydrochloride [B3925] and articaine. Mepivacaine is rapidly metabolized in liver, and is rapidly excreted via the kidneys. It has been reported that mepivacaine and procaine [P1961] have less toxicity than other local anesthetics.
References
- Pharmacokinetic and clinical pharmacological studies with mepivacaine and prilocaine (a review)
- Pharmacologic correlation between local anesthetic-induced myotoxicity and disturbances of intracellular calcium distribution (a review)
- Procaine and mepivacaine have less toxicity in vitro than other clinically used local anesthetics
- Efficacy and safety of mepivacaine compared with lidocaine in local anaesthesia in dentistry: a meta-analysis of randomised controlled trials
- Simultaneous determination of bupivacaine, mepivacaine, prilocaine and ropivacaine in human serum by liquid chromatography-tandem mass spectrometry
PubMed Literature
Product Articles
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