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Published TCIMAIL newest issue No.201
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CAS RN: 111-58-0 | Product Number: O0345
N-Oleoylethanolamine
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Purity: >98.0%(GC)
Synonyms:
- N-(2-Hydroxyethyl)oleamide
- Oleic Acid Ethanolamide
- (9Z)-N-(2-Hydroxyethyl)-9-octadecenamide
- OEA
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
56,00 €
|
2 | 6 |
|
|
| 5G |
191,00 €
|
2 | 10 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | O0345 |
Purity / Analysis Method 
|
>98.0%(GC) |
| Molecular Formula / Molecular Weight | C__2__0H__3__9NO__2 = 325.54 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 111-58-0 |
| Reaxys Registry Number | 2214880 |
| PubChem Substance ID | 468592516 |
| MDL Number | MFCD00045972 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(GC) | min. 98.0 % |
| Melting point | 63.0 to 67.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 64 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
| EC Number | 203-884-8 |
| RTECS# | RG2241000 |
Transport Information:
| HS Number | 2924190090 |
Application
N-Oleoylethanolamine (N-Oleoylethanolamide): An Endogenous Fatty Acid Amide Belong To an Important Family of Lipid-Signaling Molecules
N-Oleoylethanolamine (N-oleoylethanolamide) is an endogenous fatty acid amide, belongs to N-acylethanolamines (NAEs) which are an important family of lipid-signaling molecules such as palmitoylethanolamide [P2670]. It binds with high affinity to the peroxisome proliferator-activated receptor-α (PPAR-α), a nuclear receptor that regulates several aspects of lipid metabolism. It has recently been described as a modulator of appetite that reduces food intake and body weight gain in rat feeding models. (The product is for research purpose only.)
References
- Oleoylethanolamide Stimulates Lipolysis by Activating the Nuclear Receptor Peroxisome Proliferator-activated Receptor α (PPAR-α)
- Biological Functions and Metabolism of Oleoylethanolamide (a review)
- Regulation of food intake by oleoylethanolamide (a review)
Application
N-Oleoylethanolamine: An Endogenous Fatty Acid Amide belonging to N-Acylethanolamines (NAEs)
N-Oleoylethanolamine is an endogenous fatty acid amide, belongs to N-acylethanolamines (NAEs) which are an important family of lipid-signaling molecules such as palmitoylethanolamide [P2670]. It binds with high affinity to the peroxisome-proliferator-activated receptor-α (PPAR-α), a nuclear receptor that regulates several aspects of lipid metabolite. It has recently been described as a modulator of appetite that reduces food intake and body weight gain in rat feeding models. (The product is for research purpose only.)
References
- Oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor PPAR-α
- Cannabinoids go nuclear: evidence for activation of peroxisome proliferator-activated receptors (a review)
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