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Published TCIMAIL newest issue No.201
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CAS RN: 68572-87-2 | Product Number: P1093
9-Phenanthreneboronic Acid (contains varying amounts of Anhydride)
Purity:
Synonyms:
Product Documents:
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| Product Number | P1093 |
| Molecular Formula / Molecular Weight | C__1__4H__1__1BO__2 = 222.05 |
| Physical State (20 deg.C) | Solid |
Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 68572-87-2 |
| Reaxys Registry Number | 2976312 |
| PubChem Substance ID | 87575200 |
| MDL Number | MFCD00143524 |
Specifications
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(Neutralization titration) | 97.0 to 109.0 % |
Properties (reference)
GHS
Related Laws:
Transport Information:
| HS Number | 2931900090 |
Application
AmpC β-lactamase inhibitor
The primary resistance mechanism of microbes to β-lactam antibiotics is hydrolysis of the antibiotics by β-lactamase.1) 9-Phenanthreneboronic acid is one of boronic acid compounds having β-lactamase (AmpC) inhibition activity (Ki = 7.0 ± 1.2 μM).2)
References
- β-Lactamases and β-Lactamase Inhibitors in the 21st Century
- Structure-Based Enhancement of Boronic Acid-Based Inhibitors of AmpC β-Lactamase
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