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CAS RN: 2030-63-9 | Product Number: C2866
Clofazimine
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Purity: >98.0%(T)(HPLC)
Synonyms:
- N,5-Bis(4-chlorophenyl)-3,5-dihydro-3-(isopropylimino)phenazin-2-amine
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
61,00 €
|
Contact Us | 5 |
|
|
| 5G |
210,00 €
|
3 | 9 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | C2866 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__2__7H__2__2Cl__2N__4 = 473.40 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 2030-63-9 |
| Reaxys Registry Number | 60420 |
| PubChem Substance ID | 253661510 |
| Merck Index (14) | 2373 |
| MDL Number | MFCD00056793 |
Specifications
| Appearance | Yellow to Amber to Dark red powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
Properties (reference)
| Melting Point | 219 °C |
| Solubility in water | Insoluble |
| Solubility (soluble in) | Chloroform, Dimethylformamide |
| Solubility (slightly sol. in) | Ether, Acetone |
GHS
| Hazard Statements | H413 : May cause long lasting harmful effects to aquatic life. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. |
Related Laws:
| EC Number | 217-980-2 |
| RTECS# | SG1578000 |
Transport Information:
| HS Number | 2933998090 |
Application
Clofazimine: A Lipophilic Riminophenazine Antibiotic
Clofazimine, a lipophilic riminophenazine antimicrobial, possesses both antimycobacterial and anti-inflammatory activities， and used in the treatment of mycobacterial diseases including leprosy. The antibiotic properties of clofazimine are not fully described. However, clofazimine works by binding to the bacterial DNA, thereby inhibiting bacterial proliferation. (The product is for research purpose only.)
References
- The pharmacology, metabolism, and chemistry of clofazimine (a review)
- Antimycobacterial activities of riminophenazines (a review)
- Effective treatment of acute and chronic murine tuberculosis with liposome-encapsulated clofazimine
- Reduction of Clofazimine by Mycobacterial Type 2 NADH:Quinone Oxidoreductase: A Pathway for the Generation of Bactericidal Levels of Reactive Oxygen Species
- Clofazimine: current status and future prospects (a review)
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