Published TCIMAIL newest issue No.199
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CAS RN: 52659-56-0 | Product Number: K0059
Kirenol
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Purity: >98.0%(GC)
Synonyms:
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 25MG |
€112.00
|
Contact Us | ≥40 |
|
|
| 100MG |
€336.00
|
1 | 7 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | K0059 |
Purity / Analysis Method 
|
>98.0%(GC) |
| Molecular Formula / Molecular Weight | C__2__0H__3__4O__4 = 338.49 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 52659-56-0 |
| Reaxys Registry Number | 2336586 |
| PubChem Substance ID | 354335399 |
| MDL Number | MFCD00210519 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Specific rotation [a]20/D | -29.0 to -32.0 deg(C=0.5, pyridine) |
| Purity(GC) | min. 98.0 % |
| Melting point | 197.0 to 201.0 °C |
Properties (reference)
| Melting Point | 199 °C |
| Specific Rotation | -30° (C=0.5,Pyridine) |
GHS
Related Laws:
| RTECS# | SF7352310 |
Transport Information:
| HS Number | 2906190090 |
Application
Kirenol: A Natural Diterpenoid with Versatile Biological Activities
Kirenol is a biologically active diterpenoid isolated from Herba Siegesbeckiae. Recent studies have revealed that kirenol exhibits a variety of biological activities containing anti-oxidant, anti-inflammatory, anti-allergic, and anti-arthritic effects. (The product is for research purpose only.)
References
- Kirenol upregulates nuclear Annexin-1 which interacts with NF-κB to attenuate synovial inflammation of collagen-induced arthritis in rats
- Kirenol exerts a potent anti-arthritic effect in collagen-induced arthritis by modifying the T cells balance
- Kirenol inhibits adipogenesis through activation of the Wnt/β-catenin signaling pathway in 3T3-L1 adipocytes
- A rapid and simple RP-HPLC method for quantification of kirenol in rat plasma after oral administration and its application to pharmacokinetic study
PubMed Literature
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