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Published TCIMAIL newest issue No.198
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CAS RN: 632-93-9 | Product Number: D0558
3,5-Diethoxycarbonyl-1,4-dihydro-2,4,6-collidine
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Purity: >98.0%(GC)
Synonyms:
- 1,4-Dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylic Acid Diethyl Ester
- Diethyl 1,4-Dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate
- DDC
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 1G |
€16.00
|
1 | 36 |
|
| 5G |
€30.00
|
19 | ≥100 |
|
| 25G |
€97.00
|
1 | Contact Us |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | D0558 |
| Purity / Analysis Method | >98.0%(GC) |
| Molecular Formula / Molecular Weight | C__1__4H__2__1NO__4 = 267.33 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 632-93-9 |
| Reaxys Registry Number | 227619 |
| PubChem Substance ID | 87567213 |
| SDBS (AIST Spectral DB) | 11209 |
| MDL Number | MFCD00005950 |
Specifications
| Appearance | White to Orange to Green powder to crystal |
| Purity(GC) | min. 98.0 % |
| Melting point | 129.0 to 133.0 °C |
Properties (reference)
| Melting Point | 132 °C |
GHS
Related Laws:
| EC Number | 211-188-0 |
| RTECS# | US7979375 |
Transport Information:
| HS Number | 2933399990 |
Application
DDC: A Chronic Hepatitis (CH) Inducer in Mice
3,5-Diethoxycarbonyl-1,4-dihydrocollidine (DDC) is a liver toxic agent, and DDC-enriched diet is used to induce chronic hepatitis (CH) in mice.
References
- Atypical ductular proliferation and its inhibition by transforming growth factor β1 in the 3,5-diethoxycarbonyl-1,4-dihydrocollidine mouse model for chronic alcoholic liver disease
- K.-H. Preisegger, V. M. Factor, A. Fuchsbichler, C. Stumptner, H. Denk, S. S. Thorgeirsson, Lab. Invest. 1999, 79, 103.
- Hepatocyte cytokeratins are hyperphosphorylated at multiple sites in human alcoholic hepatitis and in a Mallory body mouse model
- The origin and liver repopulating capacity of murine oval cells
- A new xenobiotic-induced mouse model of sclerosing cholangitis and biliary fibrosis
- The role of innate immunity in the pathogenesis of preneoplasia in drug-induced chronic hepatitis based on a mouse model (a review)
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