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CAS RN: 55-98-1 | Product Number: B1022

1,4-Butanediol Dimethanesulfonate


Purity: >97.0%(T)
Synonyms:
  • Busulfan
Product Documents:
25G
$160.00
2   1   ≥40 

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Product Number B1022
Purity / Analysis Method >97.0%(T)
Molecular Formula / Molecular Weight C__6H__1__4O__6S__2 = 246.29 
Physical State (20 deg.C) Solid
Storage Temperature Room Temperature (Recommended in a cool and dark place, <15°C)
Store Under Inert Gas Store under inert gas
Condition to Avoid Moisture Sensitive
CAS RN 55-98-1
Reaxys Registry Number 1791786
PubChem Substance ID 87563973
SDBS (AIST Spectral DB) 10191
Merck Index (14) 1505
MDL Number

MFCD00007562

Specifications
Appearance White to Light yellow to Light orange powder to crystaline
Purity(Neutralization titration) min. 97.0 %
Melting point 114.0 to 118.0 °C
Properties (reference)
Melting Point 118 °C
GHS
Pictogram Pictogram Pictogram
Signal Word Danger
Hazard Statements H301 + H311 + H331 : Toxic if swallowed, in contact with skin or if inhaled.
H350 : May cause cancer.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray.
P270 : Do not eat, drink or smoke when using this product.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P271 : Use only outdoors or in a well-ventilated area.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
P362 : Take off contaminated clothing and wash before reuse.
P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth.
P302 + P352 + P312 : IF ON SKIN: Wash with plenty of water.Call a POISON CENTER/doctor if you feel unwell.
P304 + P340 + P311 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor.
P403 + P233 : Store in a well-ventilated place. Keep container tightly closed.
P405 : Store locked up.
Related Laws:
RTECS# EK1750000
Transport Information:
UN Number (DOT-AIR) UN2811
Class (DOT-AIR) 6.1
Packing Group (TCI-A) III
HS Number 2905.59.1000
Application
Busulfan: A Bifunctional Antitumor Alkylating Agent

Busulfan (1,4-butanediol dimethanesulfonate) is a bifunctional antitumor alkylating agent. Busulfan produces a greater degree of DNA-protein and DNA interstrand crosslinking, and thus may effectively induce DNA damage which may play an important role in the cytotoxicity. Busulfan has been used widely for the treatment of chronic myelogenous leukemia, and is currently used in the myeloablative conditioning regimen before hematopoietic stem cell transplantation. (The product is for research purpose only.)

References


PubMed Literature


TCIMAIL
Product Documents (Note: Some products will not have analytical charts available.)
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