Product Document Searching Made Easy by 2D Code! | TCI Chemistry News June 2026 | [TCIPracticalExample] Oxidation Reaction of Heterocycles Using... | Various analytical charts can be searched on each product detail page and Product Document Search (The kinds of analytical charts differ by product)
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 151060-21-8 | Product Number: B4354
Balofloxacin Dihydrate
×
Purity: >98.0%(T)(HPLC)
Synonyms:
- 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[3-(methylamino)-1-piperidyl]-4-oxoquinoline-3-carboxylic Acid Dihydrate
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
$69.00
|
3 | 0 | Contact Us | |
| 5G |
$208.00
|
7 | 0 | Contact Us |
* Please contact our distributors or
TCI
to order our products. The above prices do not include freight cost, customs, and other charges to the destination.
* The storage conditions are subject to change without notice.
| Product Number | B4354 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__2__0H__2__4FN__3O__4·2H__2O = 425.46 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 151060-21-8 |
| Related CAS RN
|
127294-70-6 |
| Reaxys Registry Number | 8362117 |
| PubChem Substance ID | 253661053 |
| MDL Number | MFCD00864925 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 %(as Dihydrate) |
| Water | 6.5 to 10.5 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 135 °C |
GHS
Related Laws:
| RTECS# | VB1993755 |
Transport Information:
| H.S.code* | 2933.49-000 |
Application
Balofloxacin: An 8-Methoxyfluoroquinolone Antibiotic
Balofloxacin (Q-35) is a fluoroquinolone antibiotic, in which a OMe group is substituted at the 8 position of the quinoline nucleus. In vitro, it has a broad spectrum of activity against Gram-positive bacteria (eg. Mycoplasma pneumoniae and Staphylococcus aureus including MRSA) which is almost equal to that of sparfloxacin [S0896] or tosufloxacin [T2506]. In contrast, its activity against Gram-negative bacteria is lower. In animal studies, balofloxacin do not exhibit any phototoxicity which is a toxicity of fluoroquinolone antibiotic, in general.
References
- In vitro and in vivo activities of Q-35, a new fluoroquinolone, against Mycoplasma pneumoniae
- Improved bactericidal activity of Q-35 against quinolone-resistant staphylococci
- Photostability and biological activity of fluoroquinolones substituted at the 8 position after UV irradiation
- Reduced phototoxicity of a fluoroquinolone antibacterial agent with a methoxy group at the 8 position in mice irradiated with long-wavelength UV light
- Laboratory and clinical study of balofloxacin (Q-35), a new fluoroquinolone, in urinary tract infection
- Development and validation of analytical method for estimation of Balofloxacin in bulk and pharmaceutical dosage form
PubMed Literature
Documents
Product Articles
Product Documents (Note: Some products will not have analytical charts available.)
Enter TCI Product Number
Enter KISHIDA Product Number
4-5 alphanumeric characters before the hyphen
7 alphanumeric characters
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
• The requested SDS is not available.
Specifications
The requested specifications are not available.
Please Contact Us for more information.
The requested specifications are not available.
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Incorrect Lot Number. Please input only the 7 alphanumeric characters.
• Please check that the lot number you have entered is correct. It is 4-5 alphanumeric characters before the hyphen. In particular, please check O (letter) or 0 (number) and I (letter) or 1 (number).
• If your information is correct and you are still not able to view the requested certificates, Please Contact Us for more information.
• Please check that the lot number you have entered is correct. It is 7 alphanumeric characters. In particular, please check O (letter) or 0 (number) and I (letter) or 1 (number).
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Incorrect Lot Number. Please input only the 7 alphanumeric characters.
The requested analytical chart is not available. Sorry for the inconvenience.