Product Document Searching Made Easy by 2D Code! | TCI Chemistry News November 2025 | [TCIPracticalExample] The Z-Selective Horner-Wadsworth-Emmons Reaction... | Various analytical charts can be searched on each product detail page and Product Document Search (The kinds of analytical charts differ by product)
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 866323-14-0 | Product Number: B5888
Belinostat
×
![]()
×
Purity: >98.0%(HPLC)
Synonyms:
- (E)-N-Hydroxy-3-[3-(N-phenylsulfamoyl)phenyl]acrylamide
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 25MG |
$87.00
|
3 | 8 | It can be shipped in about 2 weeks after ordering | |
| 100MG |
$285.00
|
10 | 0 | It can be shipped in about 2 weeks after ordering |
* Please contact our distributors or
TCI
to order our products. The above prices do not include freight cost, customs, and other charges to the destination.
* The storage conditions are subject to change without notice.
| Product Number | B5888 |
Purity / Analysis Method 
|
>98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__5H__1__4N__2O__4S = 318.35 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container
|
25MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 866323-14-0 |
| Reaxys Registry Number | 10087570 |
| PubChem Substance ID | 468590769 |
| MDL Number | MFCD08064035 |
Specifications
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 160 °C(dec.) |
| Maximum Absorption Wavelength | 716 nm |
GHS
Related Laws:
Transport Information:
| H.S.code* | 2935.90-000 |
Application
Belinostat: A Class I, II and IV HDAC Inhibitor
Belinostat (PXD101) is a class I, II and IV histone deacetylase (HDAC) enzyme inhibitor with a broad antineoplastic activity. HDACs catalyze the removal of acetyl groups from the N-acetylated lysine residues of histones and some non-histone proteins. Histones are the basic protein building blocks of chromatins in the nucleus of a cell, which contain DNA coiled around the histone unit. They compact DNA into a smaller volume, and also play a role in DNA replication, repair, mitosis, and gene expression. HDAC inhibitors block angiogenesis, arrest cell growth, and lead to cell-cycle arrest and apoptosis in tumor cells. Belinostat has been used for the treatment of T-cell lymphoma (PTCL). (The product is for research purpose only.)
References
- Pharmacodynamic Response and Inhibition of Growth of Human Tumor Xenografts by the Novel Histone Deacetylase Inhibitor PXD101
- Activity of PXD101, a histone deacetylase inhibitor, in preclinical ovarian cancer studies
- Belinostat: First Global Approval (a review)
- Histone deacetylase inhibitors (HDACIs). Structure-activity relationships: history and new QSAR perspectives (a review)
- LC-MS/MS assay for the quantitation of the HDAC inhibitor belinostat and five major metabolites in human plasma
Documents
Product Articles
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.