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CAS RN: 2499715-43-2 | Product Number: C3902
CPO-PFP
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Purity: >98.0%(HPLC)(qNMR)
Synonyms:
- Perfluorophenyl 4-(3-Oxocycloprop-1-en-1-yl)butanoate
- Pentafluorophenyl 4-(3-Oxo-1-cyclopropen-1-yl)butanoate
- 3-Oxo-1-cyclopropene-1-butanoic Acid 2,3,4,5,6-Pentafluorophenyl Ester
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 100MG |
$146.00
|
8 | 1 | Contact Us | |
| 500MG |
$509.00
|
10 | 8 | Contact Us |
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* The storage conditions are subject to change without notice.
| Product Number | C3902 |
Purity / Analysis Method 
|
>98.0%(HPLC)(qNMR) |
| Molecular Formula / Molecular Weight | C__1__3H__7F__5O__3 = 306.19 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Frozen (-20°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Light Sensitive,Moisture Sensitive,Heat Sensitive |
| Packaging and Container
|
100MG-Glass Bottle with Plastic Insert (View image), 500MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 2499715-43-2 |
| Reaxys Registry Number | 41868973 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(qNMR) | min. 98.0 % |
| Melting point | 64.0 to 68.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 66 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
Transport Information:
| H.S.code* | 2918.30-000 |
Application
A Derivative of Cyclopropenone (CPO) to Precisely Modify the N-Terminal Cysteine Residue
Due to the active ester moiety, CPO-PFP is used as a cyclopropenone (CPO) incorporating reagent to react with primary amines. The cyclopropenone (CPO) moiety can precisely modify the N-terminal cysteine and does not react with non-N-terminal cysteine residues or other nucleophilic side chains. After the N-terminal modification of proteins with CPO, it is possible to introduce two different modifications on a single protein targeting the cysteine residues by treating internal cysteine residues with other cysteine modification reagents.
References
- Platform for Orthogonal N-Cysteine-Specific Protein Modification Enabled by Cyclopropenone Reagents
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