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CAS RN: 51-56-9 | Product Number: H0155
Homatropine Hydrobromide
×
Purity: >99.0%(T)
Synonyms:
Product Documents:
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| 1G |
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| Product Number | H0155 |
Purity / Analysis Method 
|
>99.0%(T) |
| Molecular Formula / Molecular Weight | C__1__6H__2__1NO__3·HBr = 356.26 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Condition to Avoid | Light Sensitive |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 51-56-9 |
| Related CAS RN
|
87-00-3 |
| Reaxys Registry Number | 3742940 |
| PubChem Substance ID | 87570594 |
| Merck Index (14) | 4730 |
| MDL Number | MFCD00012676 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 99.0 % |
| Solubility in Water | almost transparency |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 212 °C |
| Solubility in water | Soluble |
| Solubility (insoluble in) | Ether |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 + H311 + H331 : Toxic if swallowed, in contact with skin or if inhaled. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust. P270 : Do not eat, drink or smoke when using this product. P271 : Use only outdoors or in a well-ventilated area. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing. P361 + P364 : Take off immediately all contaminated clothing and wash it before reuse. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P302 + P352 + P312 : IF ON SKIN: Wash with plenty of water.Call a POISON CENTER/doctor if you feel unwell. P304 + P340 + P311 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor. P403 + P233 : Store in a well-ventilated place. Keep container tightly closed. P405 : Store locked up. |
Related Laws:
| RTECS# | YM5602000 |
Transport Information:
| UN Number | UN1544 |
| Class | 6.1 |
| Packing Group | III |
| H.S.code* | 2939.79-000 |
Application
Homatropine Hydrobromide: A Muscarinic Acetylcholine Receptor Antagonist
Homatropine hydrobromide is an anticholinergic or a muscarinic acetylcholine receptor antagonist. Homatropine produces short acting cycloplegia and mydriasis when applied as eye drops. Homatropine has an action similar to atropine [A0754] [A0550 (sulfate)] and tropicamide [T1470]. (The product is for research purpose only.)
References
- Ophthalmic vehicles: The effect of methylcellulose on the penetration of homatropine hydrobromide through the cornea
- Homatropine hydrobromide (a review on the chemistry, determination methods and pharmacology of homatropine hydrobromide)
- Development and validation of a capillary zone electrophoresis method for the determination of atropine, homatropine and scopolamine in ophthalmic solutions
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