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CAS RN: 10605-02-4 | Product Number: P2138
Palmatine Chloride
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Purity: >97.0%(HPLC)
Synonyms:
- 2,3,9,10-Tetramethoxy-5,6-dihydroisoquinolino[3,2-a]isoquinolin-7-ium Chloride
- 7,8,13,13a-Tetradehydro-2,3,9,10-tetramethoxyberbinium Chloride
- 5,6-Dihydro-2,3,9,10-tetramethoxydibenzo[a,g]quinolizinium Chloride
- Fibrauretin Chloride
- Huangtengsu
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
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|---|---|---|---|---|---|
| 1G |
$136.00
|
1 | 26 | Contact Us | |
| 5G |
$412.00
|
3 | 6 | Contact Us |
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| Product Number | P2138 |
Purity / Analysis Method 
|
>97.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__1H__2__2ClNO__4 = 387.86 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 10605-02-4 |
| Reaxys Registry Number | 3833339 |
| PubChem Substance ID | 468592579 |
| MDL Number | MFCD00016656 |
Specifications
| Appearance | Light yellow to Brown powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Purity(Nonaqueous Titration) | min. 95.0 % |
| Water | max. 5.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 205 °C |
| Maximum Absorption Wavelength | 422 nm (H__2O) |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
Transport Information:
| H.S.code* | 2939.79-000 |
Application
Palmatine Chloride: An Alkaloid with a Wide Spectrum of Pharmacological Effects
Palmatine chloride, a close structural analog of berberine [B0450] [B0451], is found in Berberis vulgaris and Coptidis rhizoma which are widely used as traditional Chinese medicines (TCMs).1-3) Palmatine chloride and its analogues have been reported to exert a wide spectrum of pharmacological effects, including anti-cancer, anti-oxidation, anti-inflammatory, neuroprotection, anti-bacterial, anti-viral and regulating blood lipids.4,5) (The product is for research purpose only.)
References
- 1) Pharmacological and therapeutic effects of Berberis vulgaris and its active constituent, berberine (a review)
- 2) Coptidis rhizoma and its main bioactive components: recent advances in chemical investigation, quality evaluation and pharmacological activity (a review)
- 3) A series of strategies for solving the shortage of reference standards for multi-components determination of traditional Chinese medicine, Mahoniae Caulis as a case
- 4) Synthesis and cytotoxicity evaluation of 13-n-alkyl berberine and palmatine analogues as anticancer agents
- 5) Palmatine: A review of its pharmacology, toxicity and pharmacokinetics (a review)
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