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CAS RN: 3810-74-0 | Product Number: S0834
Streptomycin Sulfate [for Protein Research]
![Thumbnail of Streptomycin Sulfate [for Protein Research]](/medias/S0834.jpg?context=bWFzdGVyfHJvb3R8MTYxNDV8aW1hZ2UvanBlZ3xhRFprTDJnM01pODRPVE0yTmpZeE9EUXpPVGs0TDFNd09ETTBMbXB3Wnd8ZWNhZjI1OGNjZjY3YzVmOWMyNzdjZDM5MGY5OWE1NTBkYjg5ZjliMWNhOWZmZWMyN2U3ZGM0NzRlMTVmYTFhOA "Streptomycin Sulfate [for Protein Research]")
![Chemical Structure of Streptomycin Sulfate [for Protein Research]](/medias/S0834.jpg?context=bWFzdGVyfHJvb3R8NjA4Mjh8aW1hZ2UvanBlZ3xhR1pqTDJnM01DODRPVEl6TVRrME1EWTBPVEkyTDFNd09ETTBMbXB3Wnd8YjU3ZWI3ZWFjOTk2ZTY2OWZiMzA0MzFiMmRjNTRhYjkwOWQ5MzAwNjk0ZmRhNTRmZTRiODRhODljZmM1Yjc0MQ "Streptomycin Sulfate [for Protein Research]")
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![Streptomycin Sulfate [for Protein Research]](/_ui/responsive/theme-tci/images/missing_product_zoom.webp "Streptomycin Sulfate [for Protein Research]")
Purity: >95.0%(N)
Synonyms:
Product Documents:
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| Product Number | S0834 |
Purity / Analysis Method 
|
>95.0%(N) |
| Molecular Formula / Molecular Weight | C__2__1H__3__9N__7O__1__2·1^^1/__2H__2SO__4 = 728.69 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 3810-74-0 |
| Related CAS RN
|
57-92-1 |
| Reaxys Registry Number | 3894995 |
| PubChem Substance ID | 125307405 |
| Merck Index (14) | 8826 |
| MDL Number | MFCD00037023 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(with Total Nitrogen) | min. 95.0 %(calcd.on dried substance) |
| Purity(Neutralization titration) | min. 95.0 %(calcd.on dried substance) |
| Specific rotation [a]20/D | -79.0 to -88.0 deg(C=1, H2O)(calcd.on dried substance) |
| Drying loss | max. 5.0 % |
| Nucleic acid precipitation test | to pass test |
| Suitability for protein-analysis | to pass test |
| NMR | confirm to structure |
Properties (reference)
| Specific Rotation | -84° (C=1,H2O) |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| RTECS# | WK4990000 |
Transport Information:
| H.S.code* | 2941.20-000 |
Application
Streptomycin Sulfate: An Aminoglycoside Antibiotic Used for Protein Purification
Streptomycin sulfate is the first aminoglycoside antibiotic derived from the soil microbe Streptomyces griseus by Waksman and Schatz. Streptomycin sulfate has activity against aerobic Gram-negative bacteria that are not sensitive to the penicillins. Streptomycin sulfate binds to the 30S subunit of the bacterial ribosome, and then it inhibits bacterial growth by inhibiting protein synthesis. Streptomycin-resistant bacterial strains appeared soon after its introduction. However, a number of aminoglycosides have been subsequently discovered as a result of research. In addition, streptomycin sulfate is used for protein purification.
References
- Aminoglycoside uptake and mode of action - with special reference to streptomycin and gentamicin. I. Antagonists and mutants (a review)
- Aminoglycoside uptake and mode of action-with special reference to streptomycin and gentamicin. II. Effects of aminoglycosides on cells
- Dissemination of the strA-strB streptomycin-resistance genes among commensal and pathogenic bacteria from humans, animals, and plants (a review)
- Liquid chromatographic analysis of streptomycin sulfate
- Separation of nucleic acids and proteins (a review)
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Streptomycin Sulfate
| Product # | S0585 |
| CAS RN | 3810-74-0 |
| Purity / Analysis Method: | >95.0%(T)(N) |