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Published TCIMAIL newest issue No.199
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CAS RN: 226721-96-6 | Product Number: L0252
Loxoprofen Sodium Salt Dihydrate
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Purity: >98.0%(T)(HPLC)
Synonyms:
- Sodium 2-[4-[(2-Oxocyclopentyl)methyl]phenyl]propionate Dihydrate
- 2-[4-[(2-Oxocyclopentyl)methyl]phenyl]propionic Acid Sodium Salt Dihydrate
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 5G |
62,00 €
|
1 | 4 |
|
|
| 25G |
198,00 €
|
Contact Us | 32 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | L0252 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__5H__1__7NaO__3·2H__2O = 304.32 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 226721-96-6 |
| Related CAS RN
|
80382-23-6&68767-14-6 |
| Reaxys Registry Number | 5686164 |
| PubChem Substance ID | 253659596 |
| Merck Index (14) | 5589 |
| MDL Number | MFCD01745788 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Ion exchange titration) | min. 98.0 %(calcd.on anh.substance) |
| Water | 11.0 to 13.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 198 °C(dec.) |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
| RTECS# | CY1678845 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | III |
| HS Number | 2918300090 |
Application
Studies on Nonsteroidal Antiinflammatory Agents
References
- Comparison of cyclooxygenase-1 and -2 inhibitory activities of various nonsteroidal anti-inflammatory drugs using human platelets and synovial cells
- Inhibition of prostaglandin production in the inflammatory tissue by loxoprofen-sodium, an anti-inflammatory prodrug
- Inhibition of prostaglandin synthesis by sodium 2-[4-(2-oxocyclopentylmethyl)phenyl] propionate dihydrate (CS-600), a new antiinflammatory drug, and its active metabolite in vitro and in vivo
- Purification and some properties of ketone reductase forming an active metabolite of sodium 2-[4-(2-oxocyclopentylmethyl)phenyl]propionate dihydrate (loxoprofen sodium), a new antiinflammatory agent, in rabbit liver cytosol
- Identification of degradation products in loxoprofen sodium adhesive tapes by liquid chromatography-mass spectrometry and dynamic pressurized liquid extraction-solid-phase extraction coupled to liquid chromatography-nuclear magnetic resonance spectroscopy
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