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CAS RN: 77883-43-3 | Product Number: D4126
Doxazosin Mesylate
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Purity: >98.0%(HPLC)(N)
Synonyms:
- 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(1,4-benzodioxan-2-yl)carbonyl]piperazine Methanesulfonate
Product Documents:
| Size | Unit Price | Belgium | Japan* |
|---|---|---|---|
| 100MG |
€25.00
|
1 | ≥40 |
| 1G |
€156.00
|
3 | 17 |
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | D4126 |
Purity / Analysis Method 
|
>98.0%(HPLC)(N) |
| Molecular Formula / Molecular Weight | C__2__3H__2__5N__5O__5·CH__4O__3S = 547.58 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container
|
100MG-Glass Bottle with Plastic Insert (View image), 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 77883-43-3 |
| Related CAS RN
|
74191-85-8 |
| Reaxys Registry Number | 7791129 |
| PubChem Substance ID | 135727074 |
| MDL Number | MFCD00216023 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 % |
Properties (reference)
| Melting Point | 269 °C |
GHS
Related Laws:
| RTECS# | TK8044000 |
Transport Information:
| HS Number | 2933998090 |
Application
Autophagy research
References
- Doxazosin Attenuates Liver Fibrosis by Inhibiting Autophagy in Hepatic Stellate Cells via Activation of the PI3K/Akt/mTOR Signaling Pathway
- Doxazosin, a Classic Alpha 1-Adrenoceptor Antagonist, Overcomes Osimertinib Resistance in Cancer Cells via the Upregulation of Autophagy as Drug Repurposing
- Mechanisms of Action of Autophagy Modulators Dissected by Quantitative Systems Pharmacology Analysis
Application
Studies of alpha1-Adrenoceptor Antagonists in Cancer Cells
References
- Doxazosin induces apoptosis of benign and malignant prostate cells via a death receptor-mediated pathway
- Anoikis induction by quinazoline based alpha1-adrenoceptor antagonists in prostate cancer cells: antagonistic effect of bcl-2
- Doxazosin inhibits human vascular endothelial cell adhesion, migration, and invasion
PubMed Literature
Product Documents (Note: Some products will not have analytical charts available.)
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