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CAS RN: 6809-52-5 | Product Number: T2701
Teprenone [mixture of (5E,9E,13E)- and (5Z,9E,13E)- isomers]
![Chemical Structure of Teprenone [mixture of (5E,9E,13E)- and (5Z,9E,13E)- isomers]](/medias/T2701.jpg?context=bWFzdGVyfHJvb3R8MzU0MjR8aW1hZ2UvanBlZ3xhRFU1TDJnME5TODRPVEl6TlRNNU1EUTJORE13TDFReU56QXhMbXB3Wnd8ODFkMzJkNzczNGMxZTMyOGY2NTZkMzVhNWU4NTk4MWFhMWEzODI0ZGFlZmU4YjNhNDFiNzYzYzRkYTU5MDkwNA "Teprenone [mixture of (5E,9E,13E)- and (5Z,9E,13E)- isomers]")
![Thumbnail of Teprenone [mixture of (5E,9E,13E)- and (5Z,9E,13E)- isomers]](/medias/T2701.jpg?context=bWFzdGVyfHJvb3R8MTE3MDR8aW1hZ2UvanBlZ3xhRGd4TDJobU5pODRPVE0zTURBNU9UY3hNak13TDFReU56QXhMbXB3Wnd8NTQyM2UzNTUzYzI5MjRiOWE3ZTA5ZjFmMzFiYjViZTk1YjYzNTk4YjE1ZDc2NGI2NjdiM2EwNTEzNTVhOTYyZQ)
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![Teprenone [mixture of (5E,9E,13E)- and (5Z,9E,13E)- isomers]](/_ui/responsive/theme-tci/images/missing_product_zoom.webp "Teprenone [mixture of (5E,9E,13E)- and (5Z,9E,13E)- isomers]")
Purity: >95.0%(GC)
Synonyms:
- Geranylgeranylacetone [mixture of (5E,9E,13E)- and (5Z,9E,13E)- isomers]
- 6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetraen-2-one [mixture of (5E,9E,13E)- and (5Z,9E,13E)- isomers]
Product Documents:
| Size | Unit Price | Belgium | Japan* |
Shipping Information
|
|---|---|---|---|---|
| 1G |
€85.00
|
1 | 23 | |
| 5G |
€286.00
|
1 | 22 |
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | T2701 |
Purity / Analysis Method 
|
>95.0%(GC) |
| Molecular Formula / Molecular Weight | C__2__3H__3__8O = 330.56 |
| Physical State (20 deg.C) | Liquid |
| Storage Temperature
|
Frozen (<0°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| CAS RN | 6809-52-5 |
| Reaxys Registry Number | 8717724 |
| PubChem Substance ID | 125307458 |
| Merck Index (14) | 9228 |
| MDL Number | MFCD00869547 |
Specifications
| Appearance | Colorless to Light yellow to Light orange clear liquid |
| Purity(GC) | min. 95.0 %(total of isomer) |
Properties (reference)
| Boiling Point | 160 °C/0.01 mmHg |
| Specific Gravity (20/20) | 0.89 |
| Refractive Index | 1.49 |
GHS
Related Laws:
| RTECS# | RA5391300 |
Transport Information:
| HS Number | 2914199090 |
Application
Teprenone: An Agent with Potent Effects for Gastritis and Ulcers
Teprenone (or geranylgeranylacetone, GGA) has been demonstrated to show a potent anti-ulcer effect against various ulcers. Teprenone also promotes mucus synthesis and secretion in cultured gastric mucosal epithelial cells, and increases of gastric mucosal prostaglandins. Recently, teprenone has been shown to induce heat shock proteins (HSPs) in various cell types and to protect cells from apoptogenic insults. (The product is for research purpose only.)
References
- Effect of geranylgeranylacetone (GGA) on gastric lesions induced by topical aspirin plus HCl
- Geranylgeranylacetone, a Novel Anti-Ulcer Drug, Stimulates Mucus Synthesis and Secretion in Rat Gastric Cultured Cells
- Geranylgeranylacetone induces heat shock proteins in cultured guinea pig gastric mucosal cells and rat gastric mucosa
- Role of protein kinase C in geranylgeranylacetone-induced expression of heat-shock protein 72 and cardioprotection in the rat heart
- Geranylgeranylacetone ameliorates ischemic acute renal failure via induction of Hsp70
- Pharmacological targeting of the Hsp70 chaperone (a review)
PubMed Literature
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