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CAS RN: 5534-09-8 | Product Number: B4464

Beclometasone Dipropionate


Purity: >98.0%(HPLC)
Synonyms:
Documents:
1G
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Product Number B4464
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__2__8H__3__7ClO__7 = 521.05  
Physical State (20 deg.C) Solid
CAS RN 5534-09-8
Reaxys Registry Number 3638107
PubChem Substance ID 253662548
Merck Index (14) 1019
MDL Number

MFCD00135613

Specifications
Appearance White to Light yellow powder to crystal
Purity(HPLC) min. 98.0 area%
Specific rotation [a]20/D +88.0 to +94.0 deg(C=1, Dioxane)
Properties (reference)
Melting Point 208 °C(dec.)
Specific Rotation 90° (C=1,Dioxane)
Maximum Absorption Wavelength 238(EtOH) nm
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H361 : Suspected of damaging fertility or the unborn child.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
P405 : Store locked up.
Related Laws: / Compliance with laws, Regulations
RTECS# TU3805000
Transport Information:
Application
Beclomethasone Dipropionate: A Prodrug with Weak Glucocorticoid Receptor Binding Affinity

Beclomethasone dipropionate (BDP), a synthetic ant-inflammatory glucocorticoid and corticosteroid, is a prodrug with weak glucocorticoid receptor binding affinity. BDP is hydrolyzed with esterase enzymes to an active metabolite beclomethasone 17-monopropionate and minor inactive metabolites, beclomethasone 21-monopropionate and beclomethasone. BDP is freely soluble in acetone and ethanol, soluble in chloroform, and very slightly soluble in water. BDP is used for treatment of asthma and rhinitis. (The product is for research purpose only.)

References


PubMed Literature


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