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CAS RN: 1783-84-2 | Product Number: E0640
all cis-8,11,14-Eicosatrienoic Acid
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Purity: >98.0%(GC)
Synonyms:
- all cis-8,11,14-Icosatrienoic Acid
- Dihomo-γ-linolenic Acid
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 50MG |
$149.00
|
0 | 0 | Contact Us |
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| Product Number | E0640 |
Purity / Analysis Method 
|
>98.0%(GC) |
| Molecular Formula / Molecular Weight | C__2__0H__3__4O__2 = 306.49 |
| Physical State (20 deg.C) | Liquid |
| Storage Temperature
|
Frozen (-20°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Light Sensitive,Air Sensitive,Heat Sensitive |
| Packaging and Container
|
50MG-Ampule (View image) |
| CAS RN | 1783-84-2 |
| Reaxys Registry Number | 1913514 |
| PubChem Substance ID | 253662211 |
| MDL Number | MFCD00065721 |
Specifications
| Appearance | Colorless to Light yellow to Light orange clear liquid |
| Purity(GC) | min. 98.0 % |
| NMR | confirm to structure |
Properties (reference)
| Boiling Point | 200 °C |
| Flash point | 62 °C |
| Refractive Index | 1.48 |
GHS
| Signal Word | Warning |
| Hazard Statements | H227 : Combustible liquid. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P210 : Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. P280 : Wear protective gloves/ eye protection/ face protection. P370 + P378 : In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to extinguish. P403 : Store in a well-ventilated place. |
Related Laws:
| RTECS# | JX3880000 |
Transport Information:
| H.S.code* | 2916.19-000 |
Application
all cis-8,11,14-Eicosatrienoic Acid: an ω－6 fatty acid with anti-inflammatory effect
all cis-8,11,14-Eicosatrienoic acid or dihomo-γ-linolenic acid (DGLA) is a 20-carbon ω－6 fatty acid. The eicosanoid metabolites of DGLA have anti-inflammatory effect; in contrast with the eicosanoid metabolites of arachidonic acid (AA) [A0781] have inflammatory mediator effect. In addition to yielding the anti-inflammatory eicosanoids, DGLA competes with AA for cyclooxygenase (COX) and lipoxygenase, inhibiting the production of AA's eicosanoid metabolites.
References
- COX-2 inhibitors and metabolism of essential fatty acids (a review)
- Multiple roles of dihomo-γ-linolenic acid against proliferation diseases (a review)
- The fatty acids and the skin: a focus on the n-6 family of unsaturated fatty acids (a review)
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