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CAS RN: 595-33-5 | Product Number: M1949

Megestrol Acetate

Purity: >96.0%(HPLC)
  • Megestrol 17-Acetate
  • 17α-Acethoxy-6-methyl-4,6-pregnadiene-3,20-dione
  • 17α-Hydroxy-6-methyl-4,6-pregnadiene-3,20-dione 17-Acetate
3   8  
7   2  

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Product Number M1949
Purity / Analysis Method >96.0%(HPLC)
Molecular Formula / Molecular Weight C__2__4H__3__2O__4 = 384.52  
Physical State (20 deg.C) Solid
CAS RN 595-33-5
Reaxys Registry Number 1917291
PubChem Substance ID 87560201
Merck Index (14) 5805
MDL Number


Appearance White to Almost white powder to crystal
Purity(HPLC) min. 96.0 area%
Melting point 213.0 to 220.0 °C
Specific rotation [a]20/D +9.0 to +13.0 deg(C=2, CHCl3)
Properties (reference)
Melting Point 218 °C
Specific Rotation 11° (C=2,CHCl3)
Solubility (soluble in) Chloroform
Pictogram Pictogram
Signal Word Warning
Hazard Statements H351 : Suspected of causing cancer.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
P405 : Store locked up.
Related Laws: / Compliance with laws, Regulations
RTECS# TU4075000
Transport Information:
Megestrol Acetate: A Semi-Synthetic Progestational Agent

Megestrol acetate and medroxyprogesterone acetate [M1964], semi-synthetic progestational agents, are effective hormonal treatments for metastatic breast cancer in postmenopausal women. The antineoplastic effect may result from inhibition of pituitary gonadotropin production and resultant decrease in estrogen secretion. Recently, megestrol acetate is often used for the treatment of anorexia and cachexia. The precise mechanism is unknown at the present time. (The product is for research purpose only.)


PubMed Literature

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