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CAS RN: 83919-23-7 | Product Number: M2354

Mometasone Furoate


Purity: >98.0%(HPLC)
Synonyms:
  • (11β,16α)-9,21-Dichloro-17-[(2-furanylcarbonyl)oxy]-11-hydroxy-16-methylpregna-1,4-diene-3,20-dione
Documents:
200MG
$64.00
7   1  
1G
$230.00
6   2  

* Please contact our distributors or TCI to order our products. The above prices do not include freight cost, customs, and other charges to the destination.
* The storage conditions are subject to change without notice.


Product Number M2354
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__2__7H__3__0Cl__2O__6 = 521.43  
Physical State (20 deg.C) Solid
Storage Temperature 0-10°C
Condition to Avoid Heat Sensitive
CAS RN 83919-23-7
Reaxys Registry Number 4340538
PubChem Substance ID 172088987
Merck Index (14) 6241
MDL Number

MFCD00866003

Specifications
Appearance White to Light yellow powder to crystal
Purity(HPLC) min. 98.0 area%
Melting point 212.0 to 216.0 °C
Specific rotation [a]20/D +48.0 to +52.0 deg(C=0.5、MeOH)
Properties (reference)
Melting Point 214 °C(dec.)
Specific Rotation 50° (C=0.5,MeOH)
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H361 : Suspected of damaging fertility or the unborn child.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
P405 : Store locked up.
Related Laws: / Compliance with laws, Regulations
RTECS# TU3822000
Transport Information:
Application
Studies on Biological Activity of Mometasone
References

A review of the pharmacology and pharmacokinetics of inhaled fluticasone propionate and mometasone furoate

C. Crim, L. N. Pierre, P. T. Daley-Yates, Clin. Ther. 2001, 23, 1339.

In vitro glucocorticoid receptor binding and transcriptional activation by topically active glucocorticoids

C. L. Smith, W. Kreutner, Arzneim.-Forsch. 1998, 48, 956.

The inhibitory effects of topically active glucocorticoids on IL-4, IL-5, and interferon-gamma production by cultured primary CD4+ T cells

S. P. Umland, D. K. Nahrebne, S. Razac, A. Beavis, K. J. Pennline, R. W. Egan, M. M. Billah, Allergy Clin. Immunol. 1997, 100, 511.

Effects of monotherapy with intra-nasal corticosteroid or combined oral histamine and leukotriene receptor antagonists in seasonal allergic rhinitis

A. M. Wilson, L. C. Orr, E. J. Sims, B. J. Lipworth, Clin. Exp. Allergy 2001, 31, 61.

Progesterone receptor ligand binding pocket flexibility: crystal structures of norethindrone and mometasone furoate complexes

K. P. Madauss, S.-J. Deng, R. J. H. Austin, M. H. Lambert, I. McLay, J. Pritchard, S. A. Short, E. L. Stewart, I. J. Uings, S. P. Williams, J. Med. Chem. 2004, 47, 3381.


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