Maximum quantity allowed is 999
Please select the quantity
CAS RN: 192927-63-2 | Product Number: M2479
Moxifloxacin Hydrochloride Monohydrate
×
Purity: >98.0%(T)(HPLC)
Synonyms:
- 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[(4aS,7aS)-octahydro-1H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-3-quinolinecarboxylic Acid Hydrochloride Monohydrate
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 100MG |
$113.00
|
19 | ≥40 | It can be shipped in about 2 weeks after ordering | |
| 1G |
$567.00
|
32 | 4 | It can be shipped in about 2 weeks after ordering |
* Please contact our distributors or
TCI
to order our products. The above prices do not include freight cost, customs, and other charges to the destination.
* The storage conditions are subject to change without notice.
| Product Number | M2479 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__2__1H__2__4FN__3O__4·HCl·H__2O = 455.92 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container
|
100MG-Glass Bottle with Plastic Insert (View image), 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 192927-63-2 |
| Related CAS RN
|
186826-86-8&151096-09-2 |
| Reaxys Registry Number | 8377447 |
| PubChem Substance ID | 354334556 |
| Merck Index (14) | 6291 |
| MDL Number | MFCD00949117 |
Specifications
| Appearance | White to Orange to Green powder to crystaline |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| Specific rotation [a]20/D | -124 to -137 deg(C=0.5, water) |
| Water | 3.0 to 5.0 % |
Properties (reference)
| Melting Point | 240 °C(dec.) |
| Maximum Absorption Wavelength | 338 nm (H__2O) |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H341 : Suspected of causing genetic defects. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
Related Laws:
| RTECS# | VB1983750 |
Transport Information:
| H.S.code* | 2933.49-000 |
Application
Moxifloxacin Hydrochloride: A Fluoroquinolone Antibacterial with a Methoxy Group in the C-8 Position
Moxifloxacin hydrochloride (BAY 12-8039) is a synthetic fluoroquinolone antibacterial agent with in vitro activity against a wide range of Gram-positive and Gram-negative bacteria. The bactericidal action of moxifloxacin results from inhibition of the topoisomerase II (DNA gyrase) in Gram-negative bacteria and topoisomerase IV in Gram-positive bacteria required for bacterial DNA replication, transcription, repair, and recombination. It is reported that the C8-methoxy moiety contributes to enhanced activity and lower selection of resistant mutants of Gram-positive bacteria compared to the C8-H moiety. Therefore, moxifloxacin has improved activity against Gram-positive species (including staphylococci, streptococci, enterococci) compared with ciprofloxacin [ C2510, C2227 (HCl salt)]. Recently, antituberculosis activity of moxifloxacin has been reported. (The product is for research purpose only.)
References
- 1)In vitro Activity of BAY 12-8039, a New 8-Methoxyquinolone
- 2)The effect of moxifloxacin on its target topoisomerases from Escherichia coli and Staphylococcus aureus
- 3)In vitro and in vivo activities of moxifloxacin and clinafloxacin against Mycobacterium tuberculosis
- 4)Moxifloxacin: A review of its use in the management of bacterial infections
- 5)Simultaneous determination of levofloxacin, gatifloxacin and moxifloxacin in serum by liquid chromatography with column switching
- 6)Optimization of separation and determination of moxifloxacin and its related substances by RP-HPLC
- 7)Solubility of Antibiotics in Different Solvents. 1. Hydrochloride Forms of Tetracycline, Moxifloxacin, and Ciprofloxacin
PubMed Literature
Documents
Product Articles
Product Documents (Note: Some products will not have analytical charts available.)
Enter TCI Product Number
Enter KISHIDA Product Number
4-5 alphanumeric characters before the hyphen
7 alphanumeric characters
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
• The requested SDS is not available.
Specifications
The requested specifications are not available.
Please Contact Us for more information.
The requested specifications are not available.
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Incorrect Lot Number. Please input only the 7 alphanumeric characters.
• Please check that the lot number you have entered is correct. It is 4-5 alphanumeric characters before the hyphen. In particular, please check O (letter) or 0 (number) and I (letter) or 1 (number).
• If your information is correct and you are still not able to view the requested certificates, Please Contact Us for more information.
• Please check that the lot number you have entered is correct. It is 7 alphanumeric characters. In particular, please check O (letter) or 0 (number) and I (letter) or 1 (number).
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Incorrect Lot Number. Please input only the 7 alphanumeric characters.
The requested analytical chart is not available. Sorry for the inconvenience.