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CAS RN: 3737-09-5 | Product Number: D2793
Disopyramide
×
Purity: >98.0%(T)(HPLC)
Synonyms:
- 4-(Diisopropylamino)-2-phenyl-2-(2-pyridyl)butyramide
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
$58.00
|
5 | 0 | It can be shipped in about 2 weeks after ordering | |
| 5G |
$184.00
|
4 | 0 | It can be shipped in about 2 weeks after ordering |
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| Product Number | D2793 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__2__1H__2__9N__3O = 339.48 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 3737-09-5 |
| Reaxys Registry Number | 492056 |
| PubChem Substance ID | 253661200 |
| Merck Index (14) | 3360 |
| MDL Number | MFCD00057366 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 96 °C |
| Solubility in water | Slightly soluble |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| RTECS# | UR8432000 |
Transport Information:
| H.S.code* | 2933.39-000 |
Application
Disopyramide: A Class 1a Antiarrhythmic Agent
Disopyramide is a class 1a antiarrhythmic agent which interferes both with the sodium (Na+) and potassium (K+) channels, with a pharmacological profile of action similar to that of quinidine [Q0006]. Disopyramide inhibits the fast inward sodium current, and depresses the conduction velocity. Consequently, disopyramide decreases myocardial excitability. In addition, disopyramide has anticholinergic properties. (The product is for research purpose only.)
References
- A Comparison of the Antifibrillatory Actions and Effects on Intracellular Cardiac Potentials of Pronethalol, Disopyramide and Quinidine
- Effects of disopyramide on electrophysiologic properties of canine cardiac purkinje fibers
- Disopyramide: A Reappraisal of its Pharmacodynamic and Pharmacokinetic Properties, and Therapeutic Use in Cardiac Arrhythmias (a review)
- Anticholinergic effects of quinidine, disopyramide, and procainamide in isolated atrial myocytes: mediation by different molecular mechanisms (a review)
- Standards of laboratory practice: cardiac drug monitoring (a review)
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