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CAS RN: 1405-10-3 | Product Number: F0649
Fradiomycin Sulfate
Purity: >97.0%(N)
Synonyms:
						
						- Neomycin Sulfate
Product Documents:
                    
				| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time | Shipping Information   | 
|---|---|---|---|---|---|
| 25G | 
                                                $75.00 | ≥40 | ≥60 | Contact Us | 
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						* The storage conditions are subject to change without notice.
Supplemental Product Information:
This product has not been tested for potency and is guaranteed for chemical purity.
| Product Number | F0649 | 
| Purity / Analysis Method   | >97.0%(N) | 
| Molecular Formula / Molecular Weight | C__2__3H__4__6N__6O__1__3·3H__2SO__4 = 908.87 | 
| Physical State (20 deg.C) | Solid | 
| Storage Temperature   | Room Temperature (Recommended in a cool and dark place, <15°C) | 
| Store Under Inert Gas | Store under inert gas | 
| Condition to Avoid | Light Sensitive,Hygroscopic | 
| CAS RN | 1405-10-3 | 
| Related CAS RN   | 1404-04-2 | 
| Reaxys Registry Number | 9468364 | 
| PubChem Substance ID | 87560000 | 
| Merck Index (14) | 6454 | 
| MDL Number | MFCD00077833 | 
Specifications
		  | Appearance | White to Orange to Green powder to crystal | 
| Purity(with Total Nitrogen) | min. 97.0 %(calcd.on dried substance) | 
| Specific rotation [a]20/D | +55.0 to +61.0 deg(C=10, H2O)(calcd.on dried substance) | 
| Drying loss | max. 8.0 % | 
		Properties (reference)
	| Specific Rotation | 56° (C=10,H2O) | 
| Solubility in water | Soluble | 
 
						 GHS
						 | Pictogram |   | 
| Signal Word | Warning | 
| Hazard Statements | H317 : May cause an allergic skin reaction. | 
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P272 : Contaminated work clothing should not be allowed out of the workplace. P280 : Wear protective gloves. P302 + P352 : IF ON SKIN: Wash with plenty of water. P362 + P364 : Take off contaminated clothing and wash it before reuse. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. | 
 
								 Related Laws: 
							   | RTECS# | QP4375000 | 
 
						Transport Information:
							| H.S.code* | 2941.90-000 | 
			Application
		
			RNA aptamer research
		
		References
- Recognition of a cognate RNA aptamer by neomycin B: quantitative evaluation of hydrogen bonding and electrostatic interactions
- A novel RNA motif for neomycin recognition
			Application
		
			Fradiomycin or Neomycin: A Broad Spectrum Aminoglycoside Antibiotic
		
		Fradiomycin or neomycin, an aminoglycoside antibiotic, is first isolated in 1949 from the gram-positive bacillus Streptomyces fradiae. It consists of a mixture of two isomers, fradiomycin B and fradiomycin C. Fradiomycin has broad activity against Gram-negative bacteria except Pseudomonas aeruginosa and Gram-positive bacteria. It binds with bacterium ribosome 30s, and then it inhibits bacterial growth by inhibiting protein synthesis.
References
- Neomycin
- Aminoglycoside antibiotics: structure, functions and effects on in vitro plant culture and genetic transformation protocols
- Aminoglycoside-nucleic acid interactions: the case for neomycin
- Antimicrobial agents. Part II. The aminoglycosides. Streptomycin, kanamycin, gentamicin, tobramycin, amikacin, neomycin- N. S. Brewer, Mayo Clin. Proc. 1977, 52, 675.
 
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