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CAS RN: | Product Number: F1293
Ferroptocide
Purity: >90.0%(HPLC)
Synonyms:
- (2S,3aS,4S,5R,7R,8S,8aS,11R)-7-(1,3-Dioxo-2-phenyl-2,3,5,8-tetrahydro-1H-[1,2,4]triazolo[1,2-a]pyridazin-6-yl)-2,3a-dihydroxy-4,8,11-trimethyl-3-oxooctahydro-1H-4,8a-propanoazulen-5-yl 2-Chloroacetate
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Supplemental Product Information:
This material is manufactured and sold under license by the University of Illinois.
US Patent Application 62/830,384
| Product Number | F1293 |
Purity / Analysis Method
|
>90.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__3__0H__3__6ClN__3O__7 = 586.08 |
| Physical State (20 deg.C) | Solid |
Storage Temperature
|
Frozen (-20°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| Reaxys Registry Number | 34613802 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 90.0 area% |
| NMR | confirm to structure |
Properties (reference)
GHS
Related Laws:
Transport Information:
| H.S.code* | 2933.99-000 |
Application
Ferroptocide: A Thioredoxin Inhibitor
Ferroptocide has been reported as an inhibitor of thioredoxin, which is a class of small redox proteins known to be a key component of the antioxidant system in the cell. Ferroptocide has been reported to positively modulate the immune system in a mouse model of breast cancer. Therefore, ferroptocide is expected to be a useful tool for cancer research. (The product is for research purpose only.)
References
- Diverse compounds from pleuromutilin lead to a thioredoxin inhibitor and inducer of ferroptosis
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