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CAS RN: 179688-52-9 | Product Number: H1606
6-Hydroxy-7-methoxy-3H-quinazolin-4-one
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Purity: >98.0%(T)(HPLC)
Synonyms:
- 6-Hydroxy-7-methoxy-4(3H)-quinazolinone
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
$48.00
|
12 | 0 | Contact Us | |
| 5G |
$149.00
|
6 | 2 | Contact Us |
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* The storage conditions are subject to change without notice.
| Product Number | H1606 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__9H__8N__2O__3 = 192.17 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 179688-52-9 |
| Reaxys Registry Number | 8904820 |
| PubChem Substance ID | 468591972 |
| MDL Number | MFCD20547768 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 291 °C |
GHS
Related Laws:
Transport Information:
| H.S.code* | 2933.99-000 |
Application
A Synthetic Intermediate of Gefitinib
This product is used for the synthesis of gefitinib [G0546] which is a potent and selective inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase used as an antitumor agent.
References
- Improved synthesis of substituted 6,7-dihydroxy-4-quinazolineamines: tandutinib, erlotinib and gefitinib
- Synthesis and in vitro antitumor activities of novel 4-anilinoquinazoline derivatives
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