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CAS RN: 86347-15-1 | Product Number: M3314
Medetomidine Hydrochloride
Purity: >98.0%(T)(HPLC)
Synonyms:
- 5-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole Hydrochloride
- 4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole Hydrochloride
Product Documents:
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| Product Number | M3314 |
Purity / Analysis Method
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__3H__1__6N__2·HCl = 236.74 |
| Physical State (20 deg.C) | Solid |
Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Hygroscopic |
Packaging and Container
|
100MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 86347-15-1 |
| Reaxys Registry Number | 4890476 |
| PubChem Substance ID | 468592404 |
| Merck Index (14) | 5787 |
| MDL Number | MFCD06798319 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 177.0 to 181.0 °C |
| Specific rotation [a]20/D | -1.0 to +1.0 deg(C=1, H2O) |
Properties (reference)
| Melting Point | 179 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
Transport Information:
| H.S.code* | 2933.29-000 |
Application
Medetomidine Hydrochloride: A Potent α2-Adrenoceptor Agonist with Sedation and Analgesia
Medetomidine hydrochloride is a potent α2-adrenoceptor agonist which produces sedation and analgesia. Medetomidine is a mixture of R and S isomers, and the S form (or the D form known as dexmedetomidine hydrochloride [D5062]) is reported to be the active form. In animals, atipamezole (an α2-adrenoceptor antagonist) [A3259] is used for the reversal of the sedative and analgesic effects of the agonists, medetomidine and dexmedetomidine. (The product is for research purpose only.)
References
- Pharmacological profiles of medetomidine and its antagonist, atipamezole (a review)
- A review of the physiological effects of α2-agonists related to the clinical use of medetomidine in small animal practice
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