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CAS RN: 67604-48-2 | Product Number: N0072
Naringenin
×
Purity: >93.0%(T)(HPLC)
Synonyms:
- 4',5,7-Trihydroxyflavanone
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 5G |
$50.00
|
≥100 | 33 | Contact Us | |
| 25G |
$148.00
|
8 | ≥60 | Contact Us |
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| Product Number | N0072 |
Purity / Analysis Method 
|
>93.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__5H__1__2O__5 = 272.26 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 67604-48-2 |
| Reaxys Registry Number | 280888 |
| PubChem Substance ID | 87573466 |
| SDBS (AIST Spectral DB) | 7408 |
| Merck Index (14) | 6424 |
| MDL Number | MFCD00006844 |
Specifications
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(HPLC) | min. 93.0 area% |
| Purity(Neutralization titration) | min. 93.0 % |
| Ethanol | lt. 0.5 % |
| NMR | confirm to structure |
Properties (reference)
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H360 : May damage fertility or the unborn child. H350 : May cause cancer. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
Related Laws:
Transport Information:
| H.S.code* | 2932.99-000 |
Application
Research on gene transfer methods / Enhancement of lipofection efficiency
Naringenin has been reported to enhance the transfection efficiency in Colon26 and HepG2 cells.1)
Reference
- 1) Flavonoids Enhance Lipofection Efficiency and Ameliorate Cytotoxicity in Colon26 and HepG2 Cells via Oxidative Stress Regulation
- Inhibition of Quorum Sensing (QS) in Yersinia enterocolitica by an Orange Extract Rich in Glycosylated Flavanones
- The flavanone naringenin reduces the production of quorum sensing-controlled virulence factors in Pseudomonas aeruginosa PAO1
- Suppression of bacterial cell–cell signalling, biofilm formation and type III secretion system by citrus flavonoids
- 1) Effect of citrus flavonoids, Naringin and Naringenin, on metabolic syndrome and their mechanisms of action (a review)
- 2) An efficient synthesis of the potent phytoestrogens 8-prenylnaringenin and 6-(1,1-dimethylallyl)naringenin by europium(III)-catalyzed Claisen rearrangement
- 3) Total synthesis of (-)-episilvestrol and (-)-silvestrol
Application
Quorum sensing research / Biofilm research / Type III secretion system (T3SS) research
References
Application
Naringenin: A Flavanone with Numerous Biological Properties such as Antioxidant and Anti-Inflammatory Activities
Naringenin, a major flavanone, is found in the Chinese herbal medicines, tomatoes, grapefruits, and many other citrus fruits, and an aglycone form of Naringin [N0073]. It has been demonstrated to possess numerous biological properties such as antioxidant and anti-inflammatory activities.1) Naringin and naringenin inhibit some drug-metabolizing cytochrome P450 (CYP) 3A4 activity in human liver microsomes, which may result in drug-drug interactions.1) In addition, naringenin is used as a starting compound for organic synthesis.2,3) (The product is for research purpose only.)
References
PubMed Literature
Product Articles
[Research Articles] Anti-inflammatory Activity of Naringin Acyl Esters by Suppressing Nuclear Factor κB in Macrophages
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