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CAS RN: 103335-55-3 | Product Number: O0514
3-Oxo-4-aza-5α-androstan-17β-carboxylic Acid
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Purity: >98.0%(T)(HPLC)
Synonyms:
Product Documents:
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| 1G |
$83.00
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2 | 10 | Contact Us | |
| 5G |
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| Product Number | O0514 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__9H__2__9NO__3 = 319.45 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 103335-55-3 |
| Reaxys Registry Number | 5974366 |
| PubChem Substance ID | 354335802 |
| MDL Number | MFCD06411020 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| Specific rotation [a]20/D | +73.0 to +81.0 deg(C=1, pyridine) |
Properties (reference)
| Melting Point | 315 °C |
| Specific Rotation | 77° (C=1,Pyridine) |
GHS
Related Laws:
Transport Information:
| H.S.code* | 2937.90-000 |
Application
A 4-Azasteroid with 5α-Reductase Inhibitory Activity
This product is a 4-azasteroid which has the carbon atom in position 4 in the steroid ring replaced by a nitrogen atom. Reportedly, 4-azasteroids and their derivatives are effective as 5α-reductase inhibitors which are a class of medications with anti-androgenic effects.
References
- Azasteroids: structure-activity relationships for inhibition of 5α-reductase and of androgen receptor binding
- 5α-Reductase-inhibitory and antiandrogenic activities of some 4-azasteroids in the rat
- Iodotrimethylsilane-mediated 2-monohalogenation of 4-aza-5α-androstan-3-one steroids
- Synthesis and testosterone 5α-reductase-inhibitory activity of 4-aza-5α-androstane-17-carboxamide compound with an aromatic moiety in the C-17 carbamoyl group
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