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CAS RN: 14215-86-2 | Product Number: W0022
(-)-Sweroside
Purity: >98.0%(HPLC)
Synonyms:
- (4aS,5R,6S)-1-Oxo-5-vinyl-4,4a,5,6-tetrahydro-1H,3H-pyrano[3,4-c]pyran-6-yl β-D-Glucopyranoside
- (4aS,5R,6S)-5-Ethenyl-6-(β-D-glucopyranosyloxy)-4,4a,5,6-tetrahydro-1H,3H-pyrano[3,4-c]pyran-1-one
- Djalonenoside
Product Documents:
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| Product Number | W0022 |
Purity / Analysis Method
|
>98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__6H__2__2O__9 = 358.34 |
| Physical State (20 deg.C) | Solid |
Storage Temperature
|
Frozen (-20°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 14215-86-2 |
| Reaxys Registry Number | 97129 |
| PubChem Substance ID | 468593127 |
| MDL Number | MFCD09954487 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Specific rotation | -220 to -240 deg (C=0.2, methanol) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 100 °C |
| Specific Rotation | -207° (C=1,MeOH) |
| Maximum Absorption Wavelength | 250 nm (MeOH) |
GHS
Related Laws:
| RTECS# | UQ1366000 |
Transport Information:
| H.S.code* | 2938.90-000 |
Application
Sweroside: A Bioactive Herbal Ingredient Isolated from Swertia chirata
Swertia chirata has been widely used as a traditional medicine.1) Sweroside, an iridoid glycoside, is a bioactive herbal ingredient isolated from Swertia chirata. It has been reported that sweroside exhibits diverse biological activities such as anti-bacterial, free radical scavenging, anti-inflammatory, anti-tumor, and anti-osteoporotic effects.2-5) (The product is for research purpose only.)
References
- 1) Review on Swertia chirata as traditional uses to its pyhtochemistry and phrmacological activity
- 2) Bioactivity of secoiridoid glycosides from Centaurium erythraea
- 3) Effects of gentiopicroside, sweroside and swertiamarine, secoiridoids from gentian (Gentiana lutea ssp. symphyandra), on cultured chicken embryonic fibroblasts
- 4) Determination of sweroside in rat plasma and bile for oral bioavailability and hepatobiliary excretion
- 5) Protective effects of sweroside on human MG-63 cells and rat osteoblasts
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