Maintenance Notice (3:00 AM - 8:30 AM November 1, 2025 UTC): This website is scheduled to be unavailable due to maintenance. We appreciate your patience and understanding.
Product Document Searching Made Easy by 2D Code! | TCI Chemistry News October 2025 | [Product Highlights] Tetraphenylethylene Derivatives Used for... | Various analytical charts can be searched on each product detail page and Product Document Search (The kinds of analytical charts differ by product)
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 18303-04-3 | Product Number: B1648
N-(tert-Butoxycarbonyl)-p-toluenesulfonamide
×
![]()
×
Purity: >98.0%(T)(HPLC)
Synonyms:
- N-Boc-p-toluenesulfonamide
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 10G |
$80.00
|
≥40 | 6 | Contact Us | |
| 25G |
$149.00
|
32 | 0 | Contact Us |
* Please contact our distributors or
TCI
to order our products. The above prices do not include freight cost, customs, and other charges to the destination.
* The storage conditions are subject to change without notice.
| Product Number | B1648 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__2H__1__7NO__4S = 271.33 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 18303-04-3 |
| Reaxys Registry Number | 2858665 |
| PubChem Substance ID | 87564549 |
| MDL Number | MFCD00134267 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 123 °C |
GHS
Related Laws:
Transport Information:
| H.S.code* | 2935.90-000 |
Application
Sulfonamide Effective for the Introduction of Amino group
Experimental procedure: To a solution of PPh3 (6.23 g, 23.8 mmol) in THF (56 mL) under an atmosphere of nitrogen at 0 °C is added DIAD (3.85 g, 23.8 mmol). The reaction is stirred at 0 °C for 30 min before N-(tert-butoxycarbonyl)-p-toluenesulfonamide (5.37 g, 20.0 mmol) is added. The mixture is allowed to stir at 0 °C for 5 min followed by the addition of 1 (3.11 g, 19.8 mmol). The reaction is stirred at room temperature for 2.5 h before being concentrated under reduced pressure to give a crude oil. The oil is purified by flash column chromatography (silica gel, ethyl acetate:hexanes = 1:20) to generate 2 (7.54 g, 18.4 mmol, 93%) as orange oil.
References
- Iron(II) Halide Promoted Cyclization of Cyclic 2-Enynamides: Stereoselective Synthesis of Halogenated Bicyclic γ-Lactams
Application
Sulfonamide under Mitsunobu Reaction
References
- An efficient route to protected amines
PubMed Literature
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.