Maintenance Notice (10:30 PM August 23 - 3:30 AM August 24, 2025 UTC): This website is scheduled to be unavailable due to maintenance. We appreciate your patience and understanding.
Product Document Searching Made Easy by 2D Code! | TCI Life Science News August 2025 | [Product Highlights] Puberulic Acid: A Compound with... | Various analytical charts can be searched on each product detail page and Product Document Search (The kinds of analytical charts differ by product)
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 256373-96-3 | Product Number: M3396
MCC950 Sodium Salt
×
![]()
×
Purity: >95.0%(HPLC)(qNMR)
Synonyms:
- CRID3 Sodium Salt
- CP-456773 Sodium Salt
- Sodium [(1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)carbamoyl][[4-(2-hydroxypropan-2-yl)furan-2-yl]sulfonyl]amide
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 10MG |
$186.00
|
6 | 13 | Contact Us |
* Please contact our distributors or
TCI
to order our products. The above prices do not include freight cost, customs, and other charges to the destination.
* The storage conditions are subject to change without notice.
| Product Number | M3396 |
Purity / Analysis Method 
|
>95.0%(HPLC)(qNMR) |
| Molecular Formula / Molecular Weight | C__2__0H__2__3N__2NaO__5S = 426.46 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Frozen (-20°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Hygroscopic,Heat Sensitive |
| CAS RN | 256373-96-3 |
| Reaxys Registry Number | 9463223 |
| PubChem Substance ID | 468592442 |
| MDL Number | MFCD30478884 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(qNMR) | min. 95.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 239 °C |
GHS
Related Laws:
Transport Information:
| H.S.code* | 2935.90-000 |
Application
MCC 950 Sodium Salt: A Potent and Selective Small-Molecule Inhibitor of the NLRP3 Inflammasome
It has recently been reported that NLR family pyrin domain-containing protein 3 (NLRP3), a pattern recognition receptor, forms a complex called NLRP3 inflammasome in response to irritating metabolites and pathogens, and induces the production of pro-inflammatory cytokines, Interleukin (IL)-1β and IL-18. MCC950 sodium has attracted attention as a potent and selective NLRP3 inflammasome inhibitor which shows anti-inflammatory activity. (The product is for research purpose only.)
References
- A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
- The selective NLRP3-inflammasome inhibitor MCC950 reduces infarct size and preserves cardiac function in a pig model of myocardial infarction
- MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition
- Target of MCC950 in Inhibition of NLRP3 Inflammasome Activation: a Literature Review
Documents
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.