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CAS RN: 49763-96-4 | Product Number: S0905
Stiripentol
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Purity: >98.0%(GC)
Synonyms:
- 4,4-Dimethyl-1-(3,4-methylenedioxyphenyl)-1-penten-3-ol
- 1-(1,3-Benzodioxol-5-yl)-4,4-dimethyl-1-penten-3-ol
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
$133.00
|
1 | 0 | Contact Us | |
| 5G |
$439.00
|
1 | 27 | Contact Us |
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to order our products. The above prices do not include freight cost, customs, and other charges to the destination.
* The storage conditions are subject to change without notice.
| Product Number | S0905 |
| Purity / Analysis Method | >98.0%(GC) |
| Molecular Formula / Molecular Weight | C__1__4H__1__8O__3 = 234.30 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (<0°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 49763-96-4 |
| Reaxys Registry Number | 1313047 |
| PubChem Substance ID | 253660381 |
| MDL Number | MFCD00869310 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(GC) | min. 98.0 % |
| Melting point | 75.0 to 79.0 °C |
Properties (reference)
| Melting Point | 77 °C |
GHS
Related Laws:
| RTECS# | SB3393000 |
Transport Information:
| H.S.code* | 2932.99-000 |
Application
Stiripentol (STP): A Third Generation Antiepileptic Agent with Multiple Mechanisms of Action
Stiripentol (STP), a third generation antiepileptic agent, has multiple mechanisms of action. STP has recently been proved to increase the GABAergic transmission in animal experimental models. STP also acts as a potent inhibitor of CYP3A4, CYP1A2 and CYP2C19 and increases the plasma concentrations of many other antiepileptic agents. (The product is for research purpose only.)
References
- Influence of stiripentol on cytochrome P450-mediated metabolic pathways in humans: in vitro and in vivo comparison and calculation of in vivo inhibition constants
- Stiripentol, a putative antiepileptic drug, enhances the duration of opening of GABAA-receptor channels
- In vitro and in vivo inhibitory effect of stiripentol on clobazam metabolism
- The anticonvulsant stiripentol acts directly on the GABAA receptor as a positive allosteric modulator
- Stiripentol (a review)
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