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Published TCIMAIL newest issue No.201
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CAS RN: 86357-14-4 | Product Number: A3228
N-Acetyl-di-O-acetylganciclovir
Purity: >98.0%(HPLC)(N)
Synonyms:
- N-[9-[[2-(Acetyloxy)-1-[(acetyloxy)methyl]ethoxy]methyl]-6,9-dihydro-6-oxo-1H-purin-2-yl]acetamide
- Triacetylganciclovir
Product Documents:
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* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | A3228 |
Purity / Analysis Method
|
>98.0%(HPLC)(N) |
| Molecular Formula / Molecular Weight | C__1__5H__1__9N__5O__7 = 381.35 |
| Physical State (20 deg.C) | Solid |
Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 86357-14-4 |
| Reaxys Registry Number | 8229019 |
| PubChem Substance ID | 468590179 |
| MDL Number | MFCD08457700 |
Specifications
| Appearance | White to Orange to Green powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 % |
| Melting point | 172.0 to 176.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 174 °C |
| Maximum Absorption Wavelength | 278 nm |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H360 : May damage fertility or the unborn child. H340 : May cause genetic defects. H351 : Suspected of causing cancer. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
Related Laws:
Transport Information:
| HS Number | 2933599590 |
Application
A Synthetic Intermediate of Ganciclovir
This product is a synthetic intermediate of ganciclovir [G0315] which is an anti-cytomegalovirus agent.
References
- 9-{[2-Hydroxy-1-(hydroxymethyl)ethoxy]methyl}guanine: A selective inhibitor of herpes group virus replication
- A facile synthesis of 9-(1,3-dihydroxy-2-propoxymethyl)guanine (ganciclovir) from guanosine
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