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Published TCIMAIL newest issue No.198
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CAS RN: 132810-10-7 | Product Number: B4565
Blonanserin
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Purity: >98.0%(HPLC)
Synonyms:
- 2-(4-Ethyl-1-piperazinyl)-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 25MG |
€80.00
|
1 | 8 |
|
| 100MG |
€214.00
|
1 | 8 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | B4565 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__3H__3__0FN__3 = 367.51 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 132810-10-7 |
| Reaxys Registry Number | 9957203 |
| PubChem Substance ID | 253660431 |
| Merck Index (14) | 1319 |
| MDL Number | MFCD00893838 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Elemental analysis(Nitrogen) | 10.80 to 12.00 % |
| Melting point | 123.0 to 127.0 °C |
Properties (reference)
| Melting Point | 124 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. H413 : May cause long lasting harmful effects to aquatic life. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| RTECS# | GY0175140 |
Transport Information:
| HS Number | 2933599590 |
Application
Blonanserin: An Antagonist at Dopamine D2 and Serotonin 5-HT2A Receptors
Blonanserin (AD-5423) is an atypical antipsychotic agent having the properties of both a serotonin 5-HT2A and a dopamine D2 receptor antagonist. Blonanserin differs from mainly used serotonin 5-HT2A/dopamine-D2 receptor antagonists (eg: risperidone [R0087] and olanzapine [O0393]) in that it exhibits higher affinity for dopamine-D2 receptors than for serotonin 5-HT2A receptors. (The product is for research purpose only.)
References
- 1)Pharmacological profile of AD-5423, a novel antipsychotic with both potent dopamine-D2 and serotonin-S2 antagonist properties
- 2)Effect of novel atypical antipsychotic, blonanserin, on extracellular neurotransmitter level in rat prefrontal cortex
- 3)Comparative effect of lurasidone and blonanserin on cortical glutamate, dopamine, and acetylcholine efflux: role of relative serotonin (5-HT)2A and DA D2 antagonism and 5-HT1A partial agonism
- 4)Simple analysis of blonanserin, a novel antipsychotic agent, in human plasma by GC-MS
- 5)Profile of blonanserin for the treatment of schizophrenia (a review)
PubMed Literature
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