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Published TCIMAIL newest issue No.198
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CAS RN: 27200-12-0 | Product Number: D5464
Dihydromyricetin
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Purity: >97.0%(HPLC)
Synonyms:
- (2R,3R)-3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)-2,3-dihydrochromen-4-one
- Ampelopsin
- (2R,3R)-3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-4-one
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 200MG |
€96.00
|
Contact Us | 3 |
|
| 1G |
€309.00
|
10 | 19 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | D5464 |
Purity / Analysis Method 
|
>97.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__5H__1__2O__8 = 320.25 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 27200-12-0 |
| Reaxys Registry Number | 5303758 |
| PubChem Substance ID | 468591358 |
| Merck Index (14) | 579 |
| MDL Number | MFCD00189451 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Specific rotation [a]20/D | +15.5 to +17.0 deg(C=0.9, methanol) |
Properties (reference)
| Melting Point | 248 °C |
| Specific Rotation | 16° (C=0.9,MeOH) |
| Maximum Absorption Wavelength | 293 nm (MeOH) |
GHS
Related Laws:
| RTECS# | DJ2982375 |
Transport Information:
| HS Number | 2932990090 |
Application
Dihydromyricetin (Ampelopsin): A Flavonoid Component of Herbal Medicines
Dihydromyricetin (also called ampelopsin) is a flavonoid component of herbal medicines. It has been reported that dihydromyricetin has antioxidant1,2), hepatoprotective3), anti-inflammatory4,5) and anti-cancer6,7) activities. Moreover, it has been recently reported that dihydromyricetin is can be effective for the treatment of alcohol use disorders (AUDs).8) In addition, the improvement of water solubility of dihydromyricetin using polymers is reported.9) (The product is for research purpose only.)
References
- 1)Antioxidation properties and mechanism of action of dihydromyricetin from Ampelopsis grossedentata
- 2)Characterization and antioxidant activity of dihydromyricetin-lecithin complex
- 3)Hepatoprotective activity of tocha, the stems and leaves of Ampelopsis grossedentata, and ampelopsin
- 4)Suppression of Inflammatory Responses by Dihydromyricetin, a Flavonoid from Ampelopsis grossedentata, via Inhibiting the Activation of NF-κB and MAPK Signaling Pathways
- 5)Ampelopsin reduces endotoxic inflammation via repressing ROS-mediated activation of PI3K/Akt/NF-κB signaling pathways
- 6)Flavonoid ampelopsin inhibits the growth and metastasis of prostate cancer in vitro and in mice
- 7)Dihydromyricetin reduced Bcl-2 expression via p53 in human hepatoma HepG2 cells
- 8)Dihydromyricetin as a novel anti-alcohol intoxication medication
- 9)Improving the solubility of ampelopsin by solid dispersions and inclusion complexes
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