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CAS RN: 122892-31-3 | Product Number: I0948
Itopride Hydrochloride
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Purity: >98.0%(T)(HPLC)
Synonyms:
- N-[4-[2-(Dimethylamino)ethoxy]benzyl]-3,4-dimethoxybenzamide Hydrochloride
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
€16.00
|
1 | 23 |
|
|
| 5G |
€43.00
|
1 | 29 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | I0948 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__2__0H__2__6N__2O__4·HCl = 394.90 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 122892-31-3 |
| Related CAS RN
|
122898-67-3 |
| Reaxys Registry Number | 5369226 |
| PubChem Substance ID | 253662451 |
| Merck Index (14) | 5244 |
| MDL Number | MFCD00881710 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 192.0 to 196.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 194 °C |
| Maximum Absorption Wavelength | 258 nm (MeOH) |
| Solubility (slightly sol. in) | Ethanol |
GHS
Related Laws:
| RTECS# | CV4552000 |
Transport Information:
| HS Number | 2924297099 |
Application
Itopride Hydrochloride: A Water Soluble D2-Dopamine Receptor Antagonist
Itopride hydrochloride (HSR-803) is a water soluble D2-dopamine receptor antagonist and has a gastrokinetic effect. (The product is for research purpose only.)
References
- A novel water-soluble dopamine-2 antagonist with anticholinesterase activity in gastrointestinal motor activity. Comparison with domperidone and neostigmine
- Gastroprokinetic effect of a new benzamide derivative itopride and its action mechanisms in conscious dogs
- The involvement of flavin-containing monooxygenase but not CYP3A4 in metabolism of itopride hydrochloride, a gastroprokinetic agent: comparison with cisapride and mosapride citrate
- Stimulatory action of itopride hydrochloride on colonic motor activity in vitro and in vivo
- Chromatographic determination of itopride hydrochloride in the presence of its degradation products
- Determination of pantoprazole, rabeprazole, esomeprazole, domperidone and itopride in pharmaceutical products by reversed phase liquid chromatography using single mobile phase
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