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CAS RN: 6150-58-9 | Product Number: L0319
Lycorine Hydrochloride Monohydrate
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Purity: >98.0%(T)(HPLC)
Synonyms:
- (1S,2S,12bS,12cS)-2,4,5,7,12b,12c-Hexahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol Hydrochloride Monohydrate
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 25MG |
€93.00
|
Contact Us | 24 |
|
|
| 100MG |
€250.00
|
Contact Us | 15 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | L0319 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__6H__1__7NO__4·HCl·H__2O = 341.79 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 6150-58-9 |
| Related CAS RN
|
2188-68-3 |
| Reaxys Registry Number | 6105700 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Specific rotation [a]20/D | +41.0 to +45.0 deg(C=2.9, water) |
| Water | max. 7.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 215 °C(dec.) |
| Specific Rotation | 43° (C=2.9,H2O) |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
| RTECS# | OL2910000 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | III |
| HS Number | 2934999090 |
Application
Lycorine Hydrochloride: The Major Bioactive Alkaloid Found in Amaryllidaceae Family Plant
Lycorine hydrochloride is the major bioactive alkaloid found in Amaryllidaceae family plant, a represent traditional Chinese medicinal herb. Lycorine and its derivatives have been shown to have various biological activities, including anti-leukemia, anti-tumor, anti-angiogenesis, anti-virus, anti-bacteria, anti-inflammation, and anti-malaria. They also exert many biological functions, such as inhibition of acetylcholinesterase. (The product is for research purpose only.)
References
- Lycorine, the Main Phenanthridine Amaryllidaceae Alkaloid, Exhibits Significant Antitumor Activity in Cancer Cells That Display Resistance to Proapoptotic Stimuli: An Investigation of Structure-Activity Relationship and Mechanistic Insight
- Anticancer evaluation of structurally diverse Amaryllidaceae alkaloids and their synthetic derivatives (a review)
- Lycorine and its derivatives for anticancer drug design (a review)
- Multiple biological functions and pharmacological effects of lycorine (a review)
- LCMS and GCMS for the screening of alkaloids in natural and in vitro extracts of Leucojum aestivum
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