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Published TCIMAIL newest issue No.201
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CAS RN: 96829-58-2 | Product Number: O0381
Orlistat
Purity: >97.0%(HPLC)(N)
Synonyms:
- N-Formyl-L-leucine (1S)-1-[[(2S,3S)-3-Hexyl-4-oxo-2-oxetanyl]methyl]dodecyl Ester
Product Documents:
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| Product Number | O0381 |
Purity / Analysis Method
|
>97.0%(HPLC)(N) |
| Molecular Formula / Molecular Weight | C__2__9H__5__3NO__5 = 495.75 |
| Physical State (20 deg.C) | Solid |
Storage Temperature
|
Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
Packaging and Container
|
100MG-Glass Bottle with Plastic Insert (View image), 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 96829-58-2 |
| Reaxys Registry Number | 3658031 |
| PubChem Substance ID | 135727048 |
| Merck Index (14) | 6869 |
| MDL Number | MFCD05662360 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Purity(with Total Nitrogen) | min. 97.0 % |
| Melting point | 43.0 to 47.0 °C |
| Specific rotation [a]20/D | -33.0 to -36.0 deg(C=1, CHCL3) |
Properties (reference)
| Melting Point | 45 °C |
| Specific Rotation | -35° (C=1,CHCl3) |
| Solubility (soluble in) | Chloroform |
GHS
Related Laws:
| RTECS# | OH3167600 |
Transport Information:
| HS Number | 2932209090 |
Application
Studies of Lipase Inhibitors
References
- Inhibition of pancreatic lipase in vitro by the covalent inhibitor tetrahydrolipstatin
- P. Hadvary, H. Lengsfeld, H. Wolfer, Biochem. J. 1988, 256, 357.
- The lipase inhibitor tetrahydrolipstatin binds covalently to the putative active site serine of pancreatic lipase
- P. Hadvary, W. Sidler, W. Meister, W. Vetter, H. Wolfer, J. Biol. Chem. 1991, 266, 2021.
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